Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-Xre |
| Location | 975494..976426 | Replicon | plasmid pSymB |
| Accession | NZ_CP026527 | ||
| Organism | Sinorhizobium meliloti strain AK21 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | C3L21_RS30860 | Protein ID | WP_127518759.1 |
| Coordinates | 975494..976048 (-) | Length | 185 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | H0G7T7 |
| Locus tag | C3L21_RS30865 | Protein ID | WP_003534594.1 |
| Coordinates | 976055..976426 (-) | Length | 124 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C3L21_RS30840 | 971026..971892 | + | 867 | WP_010975580.1 | sulfate ABC transporter permease subunit CysT | - |
| C3L21_RS30845 | 971882..972757 | + | 876 | WP_127518760.1 | sulfate ABC transporter permease subunit CysW | - |
| C3L21_RS30850 | 972773..973876 | + | 1104 | WP_010975578.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| C3L21_RS30855 | 973988..975358 | + | 1371 | WP_003537831.1 | FAD-binding oxidoreductase | - |
| C3L21_RS30860 | 975494..976048 | - | 555 | WP_127518759.1 | RES family NAD+ phosphorylase | Toxin |
| C3L21_RS30865 | 976055..976426 | - | 372 | WP_003534594.1 | DUF2384 domain-containing protein | Antitoxin |
| C3L21_RS30870 | 976503..977288 | - | 786 | WP_003534600.1 | crotonase/enoyl-CoA hydratase family protein | - |
| C3L21_RS30875 | 977285..978154 | - | 870 | WP_127518758.1 | hydroxymethylglutaryl-CoA lyase | - |
| C3L21_RS30880 | 978151..980139 | - | 1989 | WP_015243150.1 | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | - |
| C3L21_RS30885 | 980156..980539 | - | 384 | WP_010975573.1 | RidA family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Mobilizable plasmid | - | htpB | 1..1676618 | 1676618 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 185 a.a. Molecular weight: 20463.34 Da Isoelectric Point: 6.4901
>T95054 WP_127518759.1 NZ_CP026527:c976048-975494 [Sinorhizobium meliloti]
MRKHIPPASRPDPEPTSPVEPITLWRAFVPRWAHMTLSGAGAARFGGRWNPIGMPAIYAARELSTAWAEYNQGFVQHPAL
IVQLELRGARLADLTDASVLLELGVDEAIHRCEWRDALDKGAVPETHRLQSELLARDYHGVIYPSFMSPGGTCVALWRWN
GAEEPRLDVIDPDGRLPKSPASWV
MRKHIPPASRPDPEPTSPVEPITLWRAFVPRWAHMTLSGAGAARFGGRWNPIGMPAIYAARELSTAWAEYNQGFVQHPAL
IVQLELRGARLADLTDASVLLELGVDEAIHRCEWRDALDKGAVPETHRLQSELLARDYHGVIYPSFMSPGGTCVALWRWN
GAEEPRLDVIDPDGRLPKSPASWV
Download Length: 555 bp
>T95054 NZ_CP026527:c976048-975494 [Sinorhizobium meliloti]
ATGAGGAAACACATTCCGCCCGCATCGCGACCCGATCCGGAACCGACGTCGCCGGTCGAGCCGATAACGCTCTGGCGCGC
CTTCGTTCCGCGCTGGGCACATATGACGCTATCCGGCGCGGGTGCCGCTCGCTTCGGTGGCCGCTGGAACCCGATCGGCA
TGCCTGCGATTTATGCTGCGCGCGAGCTTTCCACTGCCTGGGCTGAATATAATCAGGGTTTCGTGCAGCATCCGGCGCTC
ATCGTGCAGCTCGAGTTGCGCGGGGCGAGGCTCGCGGACCTCACGGATGCCAGCGTTCTTCTGGAGCTTGGTGTGGATGA
GGCGATCCATCGCTGCGAATGGCGTGATGCGCTCGACAAAGGCGCGGTGCCGGAGACCCACAGGCTGCAGTCGGAGCTTC
TGGCGCGCGACTATCACGGGGTGATCTATCCATCCTTCATGTCGCCCGGCGGCACCTGCGTCGCGCTCTGGCGCTGGAAC
GGTGCGGAAGAACCGCGTCTCGACGTCATCGATCCCGATGGCCGGCTGCCGAAATCGCCCGCCTCATGGGTTTGA
ATGAGGAAACACATTCCGCCCGCATCGCGACCCGATCCGGAACCGACGTCGCCGGTCGAGCCGATAACGCTCTGGCGCGC
CTTCGTTCCGCGCTGGGCACATATGACGCTATCCGGCGCGGGTGCCGCTCGCTTCGGTGGCCGCTGGAACCCGATCGGCA
TGCCTGCGATTTATGCTGCGCGCGAGCTTTCCACTGCCTGGGCTGAATATAATCAGGGTTTCGTGCAGCATCCGGCGCTC
ATCGTGCAGCTCGAGTTGCGCGGGGCGAGGCTCGCGGACCTCACGGATGCCAGCGTTCTTCTGGAGCTTGGTGTGGATGA
GGCGATCCATCGCTGCGAATGGCGTGATGCGCTCGACAAAGGCGCGGTGCCGGAGACCCACAGGCTGCAGTCGGAGCTTC
TGGCGCGCGACTATCACGGGGTGATCTATCCATCCTTCATGTCGCCCGGCGGCACCTGCGTCGCGCTCTGGCGCTGGAAC
GGTGCGGAAGAACCGCGTCTCGACGTCATCGATCCCGATGGCCGGCTGCCGAAATCGCCCGCCTCATGGGTTTGA
Antitoxin
Download Length: 124 a.a. Molecular weight: 13113.26 Da Isoelectric Point: 9.9996
>AT95054 WP_003534594.1 NZ_CP026527:c976426-976055 [Sinorhizobium meliloti]
MMAVDFQIPAARFGDDHSPFLSARLVADRLGVTLAELAKLIGVARNTLTAKSGARKVDSALSKVVRILAMASEMAGDEAR
AVIWFKHQPIPGWAGKTAFDLVGEGKADKVLAYLESVRAGVYA
MMAVDFQIPAARFGDDHSPFLSARLVADRLGVTLAELAKLIGVARNTLTAKSGARKVDSALSKVVRILAMASEMAGDEAR
AVIWFKHQPIPGWAGKTAFDLVGEGKADKVLAYLESVRAGVYA
Download Length: 372 bp
>AT95054 NZ_CP026527:c976426-976055 [Sinorhizobium meliloti]
ATGATGGCCGTTGATTTCCAGATACCTGCAGCCCGTTTCGGGGACGATCATTCCCCGTTTCTCTCGGCCCGCCTTGTCGC
CGACCGGTTGGGCGTCACGCTCGCCGAACTCGCCAAGCTGATCGGTGTCGCCCGCAATACGCTGACGGCGAAATCCGGCG
CCCGGAAGGTCGACAGCGCCTTGAGCAAGGTCGTCCGCATCCTCGCCATGGCTTCCGAAATGGCGGGCGACGAAGCCCGC
GCCGTCATCTGGTTCAAGCACCAGCCTATCCCCGGCTGGGCCGGCAAGACGGCGTTCGATCTGGTCGGCGAGGGCAAGGC
CGACAAGGTGCTCGCCTATCTCGAATCGGTACGTGCCGGCGTCTACGCTTAA
ATGATGGCCGTTGATTTCCAGATACCTGCAGCCCGTTTCGGGGACGATCATTCCCCGTTTCTCTCGGCCCGCCTTGTCGC
CGACCGGTTGGGCGTCACGCTCGCCGAACTCGCCAAGCTGATCGGTGTCGCCCGCAATACGCTGACGGCGAAATCCGGCG
CCCGGAAGGTCGACAGCGCCTTGAGCAAGGTCGTCCGCATCCTCGCCATGGCTTCCGAAATGGCGGGCGACGAAGCCCGC
GCCGTCATCTGGTTCAAGCACCAGCCTATCCCCGGCTGGGCCGGCAAGACGGCGTTCGATCTGGTCGGCGAGGGCAAGGC
CGACAAGGTGCTCGCCTATCTCGAATCGGTACGTGCCGGCGTCTACGCTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|