Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 27478..27983 Replicon plasmid unnamed2
Accession NZ_CP026518
Organism Deinococcus sp. NW-56

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag C3K08_RS15820 Protein ID WP_104992425.1
Coordinates 27723..27983 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C3K08_RS15815 Protein ID WP_104992424.1
Coordinates 27478..27726 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3K08_RS18095 22687..23493 - 807 WP_158680024.1 hypothetical protein -
C3K08_RS15785 23621..23845 - 225 WP_104992420.1 IS3 family transposase -
C3K08_RS15795 24221..25006 + 786 WP_104991621.1 IS630 family transposase -
C3K08_RS15800 25115..26194 + 1080 WP_104992421.1 transposase -
C3K08_RS15805 26575..26784 - 210 WP_104992422.1 DUF2263 domain-containing protein -
C3K08_RS15810 26781..27434 - 654 WP_158680025.1 ASCH domain-containing protein -
C3K08_RS15815 27478..27726 + 249 WP_104992424.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C3K08_RS15820 27723..27983 + 261 WP_104992425.1 Txe/YoeB family addiction module toxin Toxin
C3K08_RS15825 28305..28526 + 222 WP_104992426.1 transposase -
C3K08_RS15830 28714..29481 + 768 WP_158680026.1 hypothetical protein -
C3K08_RS15835 29478..30011 + 534 WP_104992428.1 DUF1788 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..373067 373067


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10311.73 Da        Isoelectric Point: 8.5686

>T95040 WP_104992425.1 NZ_CP026518:27723-27983 [Deinococcus sp. NW-56]
MRLVFSPEAWEDYLFWQEQGGKTLRKINELIRATTRDPLSGPGKPEPLRHQLQGWWSRRITLEHRFVYRVSGDDLLIASL
RFHYED

Download         Length: 261 bp

>T95040 NZ_CP026518:27723-27983 [Deinococcus sp. NW-56]
ATGAGACTGGTCTTCTCCCCGGAAGCGTGGGAGGACTACCTGTTCTGGCAGGAGCAAGGCGGCAAGACCTTGAGGAAGAT
CAACGAACTCATCCGGGCCACCACCCGCGACCCGTTGAGCGGCCCCGGCAAACCTGAACCGCTGCGGCATCAGCTTCAGG
GCTGGTGGTCGCGGCGCATCACCCTGGAACACCGCTTCGTGTACCGCGTGAGCGGGGATGACCTGCTGATCGCCAGCCTG
CGCTTCCATTACGAGGATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9207.39 Da        Isoelectric Point: 5.0893

>AT95040 WP_104992424.1 NZ_CP026518:27478-27726 [Deinococcus sp. NW-56]
MRSVTYTKLRQNLAATMDEVIDNHDPVIVTRGERAVVVMSLEDFNSWQETAHLLGTPANARRLLRSIAALEAGRGEERDL
TE

Download         Length: 249 bp

>AT95040 NZ_CP026518:27478-27726 [Deinococcus sp. NW-56]
ATGCGATCGGTAACCTATACCAAGCTGCGGCAGAATCTCGCGGCCACCATGGACGAGGTGATCGACAACCACGATCCGGT
GATCGTAACGCGGGGTGAGCGGGCCGTAGTGGTCATGAGCCTGGAGGACTTCAACTCCTGGCAGGAAACCGCGCACCTGT
TGGGGACGCCGGCCAACGCCCGCCGCCTCCTGAGGTCTATCGCGGCCCTGGAGGCTGGACGGGGCGAGGAACGGGACCTG
ACCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References