Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3699974..3700196 Replicon chromosome
Accession NZ_CP026345
Organism Escherichia coli strain 8A

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag C2R18_RS19225 Protein ID WP_000141634.1
Coordinates 3699974..3700081 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3700130..3700196 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2R18_RS19200 3695227..3695979 - 753 Protein_3513 cellulose biosynthesis protein BcsQ -
C2R18_RS19205 3695991..3696179 - 189 WP_001063318.1 YhjR family protein -
C2R18_RS19210 3696452..3698023 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
C2R18_RS19215 3698020..3698211 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
C2R18_RS19220 3698208..3699887 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
C2R18_RS19225 3699974..3700081 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3700130..3700196 + 67 - - Antitoxin
C2R18_RS19240 3700557..3701828 + 1272 WP_001295225.1 transporter -
C2R18_RS19245 3701858..3702862 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
C2R18_RS19250 3702859..3703842 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
C2R18_RS19255 3703853..3704755 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T94008 WP_000141634.1 NZ_CP026345:c3700081-3699974 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T94008 NZ_CP026345:c3700081-3699974 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT94008 NZ_CP026345:3700130-3700196 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References