Detailed information of TA system TA093835

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 1840875..1841575
• Replicon: chromosome
• Accession: NZ_CP026332
• Organism: Pseudomonas sp. XWY-1

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: PRJ_RS08685
• Protein ID: WP_023389615.1
• Coordinates: 1840875..1841171 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: A0A2L1I9E4
• Locus tag: PRJ_RS08690
• Protein ID: WP_019437852.1
• Coordinates: 1841174..1841575 (+)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PRJ_RS08665	1836866..1838044	-	1179	WP_064493133.1	efflux RND transporter periplasmic adaptor subunit	-
PRJ_RS08670	1838258..1838734	+	477	WP_104961115.1	sigma-70 family RNA polymerase sigma factor	-
PRJ_RS08675	1838903..1839382	+	480	WP_019437855.1	hypothetical protein	-
PRJ_RS08680	1839455..1840780	+	1326	WP_104961116.1	MFS transporter	-
PRJ_RS08685	1840875..1841171	+	297	WP_023389615.1	type II toxin-antitoxin system MqsR family toxin	Toxin
PRJ_RS08690	1841174..1841575	+	402	WP_019437852.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
PRJ_RS08695	1841695..1843377	-	1683	WP_023389616.1	electron transfer flavoprotein-ubiquinone oxidoreductase	-
PRJ_RS08700	1843913..1844662	+	750	WP_003254232.1	electron transfer flavoprotein subunit beta/FixA family protein	-
PRJ_RS08705	1844663..1845592	+	930	WP_010954958.1	FAD-binding protein	-
PRJ_RS08710	1845668..1846489	+	822	WP_104961117.1	transporter substrate-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (2-97)

Antitoxin

• Antitoxin MqsA/HigA-2 (1-131)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11165.97 Da
• Isoelectric Point: 8.8385

>T93835 WP_023389615.1 NZ_CP026332:1840875-1841171 [Pseudomonas sp. XWY-1]
MEKRTPHCPLERVRALVGAGRISPTTASLRGAQALGMEYADMLEVITGLERRDFYKSMTSYADHRVWQDVYRPLTVKGYL
YLKLSVVDDALIVSFKEL

Nucleotide

• Length: 297 bp

>T93835 NZ_CP026332:1840875-1841171 [Pseudomonas sp. XWY-1]
ATGGAAAAGAGAACGCCTCATTGCCCGCTGGAGCGGGTAAGAGCACTGGTGGGCGCTGGCCGCATCAGCCCTACAACCGC
TTCCTTACGAGGCGCTCAGGCCTTGGGAATGGAATATGCGGACATGCTGGAGGTCATCACCGGTCTGGAGCGCAGAGATT
TCTACAAAAGCATGACCAGTTATGCCGACCACCGCGTTTGGCAAGATGTCTATCGGCCGCTTACGGTAAAGGGATATCTG
TACCTGAAACTGTCAGTGGTAGATGACGCGCTCATCGTGTCTTTCAAGGAGTTGTGA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14818.86 Da
• Isoelectric Point: 4.6580

>AT93835 WP_019437852.1 NZ_CP026332:1841174-1841575 [Pseudomonas sp. XWY-1]
MRCPICGGAELALDTQDMPYRYKGESTLIPDVTGDYCSVCGEAVLSHDEAMRVSDLMSAFNRQVNALDVDPDFIVSVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTKPPVALIKLFKLLDRHPELFEEVRTA

Nucleotide

• Length: 402 bp

>AT93835 NZ_CP026332:1841174-1841575 [Pseudomonas sp. XWY-1]
ATGAGATGCCCAATTTGCGGAGGTGCCGAGCTCGCGCTAGACACTCAGGACATGCCCTACCGGTATAAGGGGGAATCGAC
CCTGATACCTGATGTGACGGGCGATTACTGTTCTGTCTGTGGTGAGGCAGTGCTAAGTCATGACGAGGCTATGCGAGTCA
GCGATCTGATGTCTGCCTTCAATCGCCAAGTCAATGCTCTAGACGTTGATCCCGATTTCATCGTTTCCGTACGCAAGAAA
TTTGATCTGGATCAGCGGGAGGCTGGGGAAATATTCGGTGGAGGAGTCAATGCTTTTTCACGTTATGAGAATGGCAAAAC
CAAACCGCCGGTGGCGCTGATCAAATTGTTCAAGTTGCTCGACCGTCACCCGGAGCTCTTTGAGGAAGTCAGGACTGCGT
GA

Structures

Antitoxin

• AlphaFold DB: A0A2L1I9E4