93756

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 4665293..4665816 Replicon chromosome
Accession NZ_CP026265
Organism Aminobacter sp. MSH1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CO731_RS23030 Protein ID WP_108608975.1
Coordinates 4665293..4665565 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CO731_RS23035 Protein ID WP_108608976.1
Coordinates 4665565..4665816 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO731_RS23010 4660442..4662220 - 1779 WP_108608971.1 acyl-CoA dehydrogenase -
CO731_RS23015 4662389..4662634 + 246 WP_108608972.1 hypothetical protein -
CO731_RS23020 4662686..4663882 + 1197 WP_108608973.1 muramidase -
CO731_RS23025 4663906..4665183 - 1278 WP_108608974.1 phosphoribosylamine--glycine ligase -
CO731_RS23030 4665293..4665565 - 273 WP_108608975.1 Txe/YoeB family addiction module toxin Toxin
CO731_RS23035 4665565..4665816 - 252 WP_108608976.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CO731_RS23040 4665917..4666900 + 984 WP_108608977.1 4-hydroxybenzoate octaprenyltransferase -
CO731_RS23045 4666901..4667467 - 567 WP_108608978.1 hypothetical protein -
CO731_RS23050 4667635..4669065 - 1431 WP_108608979.1 FAD-binding oxidoreductase -
CO731_RS23055 4669081..4670019 - 939 WP_199914651.1 threonylcarbamoyl-AMP synthase -
CO731_RS23060 4670221..4670625 + 405 WP_108608981.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10571.02 Da        Isoelectric Point: 9.5786

>T93756 WP_108608975.1 NZ_CP026265:c4665565-4665293 [Aminobacter sp. MSH1]
MLIIFSEASWSDYLFWQQSDRTVCNRINELIKDTRRSPFVGIGKPEPLSGNFAGFWSRRITREHRLVYRVTGKGDTQALE
IAACRYHYDK

Download         Length: 273 bp

>T93756 NZ_CP026265:c4665565-4665293 [Aminobacter sp. MSH1]
ATGCTGATCATTTTTTCGGAAGCCTCCTGGTCCGATTATCTGTTCTGGCAGCAGAGCGATAGGACCGTTTGCAACCGCAT
CAATGAACTCATCAAGGATACTAGGCGCTCGCCCTTCGTCGGCATTGGCAAGCCCGAGCCGCTTTCCGGCAATTTTGCCG
GCTTCTGGTCGCGCCGTATCACGCGCGAGCACCGGCTCGTCTATCGGGTGACCGGCAAGGGCGATACCCAGGCCTTGGAG
ATTGCCGCCTGCCGCTATCATTACGACAAGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9528.81 Da        Isoelectric Point: 4.6941

>AT93756 WP_108608976.1 NZ_CP026265:c4665816-4665565 [Aminobacter sp. MSH1]
MTYVTLTELRANMAKHFDKVEEDRIELVVTRQNHEPMVVMALSELEGLRETLHLLSSRANAEHLQRSIDELNAGTGLERD
LIE

Download         Length: 252 bp

>AT93756 NZ_CP026265:c4665816-4665565 [Aminobacter sp. MSH1]
ATGACGTATGTCACGCTTACCGAACTTCGCGCCAACATGGCCAAGCATTTCGACAAGGTCGAGGAAGACCGGATCGAATT
GGTGGTGACTAGGCAGAATCATGAGCCGATGGTGGTCATGGCCCTGTCCGAGCTTGAGGGGCTTCGCGAAACCCTGCATT
TGCTGAGTTCGCGTGCCAACGCCGAGCATCTCCAGCGCTCCATCGATGAACTCAATGCTGGCACCGGCCTCGAACGAGAC
CTCATCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References