Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1833965..1834781 Replicon chromosome
Accession NZ_CP026216
Organism Citrobacter sp. CFNIH10

Toxin (Protein)


Gene name yhaV Uniprot ID A0A3S7D6F0
Locus tag C2U53_RS12260 Protein ID WP_042999109.1
Coordinates 1834305..1834781 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A3Q8DNJ3
Locus tag C2U53_RS12255 Protein ID WP_042999108.1
Coordinates 1833965..1834300 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2U53_RS12235 1831184..1831810 + 627 WP_042999104.1 dimethylsulfoxide reductase subunit B -
C2U53_RS12240 1831803..1832576 + 774 WP_044257303.1 dimethyl sulfoxide reductase anchor subunit -
C2U53_RS12245 1832621..1833217 + 597 WP_042999106.1 molecular chaperone -
C2U53_RS12250 1833214..1833750 + 537 WP_042999107.1 ferredoxin-type protein NapF -
C2U53_RS12255 1833965..1834300 + 336 WP_042999108.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
C2U53_RS12260 1834305..1834781 + 477 WP_042999109.1 type II toxin-antitoxin system YhaV family toxin Toxin
C2U53_RS12265 1835205..1835735 + 531 WP_042999110.1 type 1 fimbrial protein -
C2U53_RS12270 1835903..1836352 + 450 WP_086513030.1 type 1 fimbrial protein -
C2U53_RS12275 1836416..1838890 + 2475 WP_044257386.1 fimbria/pilus outer membrane usher protein -
C2U53_RS12280 1838933..1839676 + 744 WP_044264050.1 molecular chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(15-110)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 18237.84 Da        Isoelectric Point: 8.8956

>T93695 WP_042999109.1 NZ_CP026216:1834305-1834781 [Citrobacter sp. CFNIH10]
MDFPTWLNGWTIYAHPCFIDQYNALVARVEDLKHRFPDPIVFQKKKETKVLAHLLKSIANITHEPRASVYRPGDSIGKAY
TDWSRAKFGGGRYRLFFRYSLESKIIVIAWVNDEGPLRTYGSKTDAYKIFGKMLDEGNPPDDWLSLLQACQNDGKEHL

Download         Length: 477 bp

>T93695 NZ_CP026216:1834305-1834781 [Citrobacter sp. CFNIH10]
ATGGATTTTCCCACATGGCTGAACGGGTGGACGATCTACGCTCATCCCTGTTTTATCGATCAATACAACGCGCTGGTCGC
ACGTGTTGAAGACCTTAAGCACAGGTTTCCAGATCCCATTGTTTTCCAGAAGAAGAAAGAGACCAAGGTGCTGGCGCATT
TATTGAAATCCATTGCCAACATTACCCACGAACCCCGAGCTTCTGTTTACCGGCCTGGTGACAGTATAGGGAAAGCTTAT
ACAGACTGGTCGAGAGCGAAGTTTGGTGGAGGACGGTATCGCTTATTTTTCCGTTATAGTCTCGAGAGTAAGATCATTGT
CATCGCATGGGTGAATGATGAAGGGCCATTGCGCACCTACGGCAGCAAGACCGATGCCTATAAGATTTTCGGGAAAATGC
TCGATGAGGGAAATCCACCCGACGACTGGCTAAGTTTGCTTCAGGCTTGTCAAAACGACGGGAAGGAACATCTTTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12505.83 Da        Isoelectric Point: 4.1876

>AT93695 WP_042999108.1 NZ_CP026216:1833965-1834300 [Citrobacter sp. CFNIH10]
MFAYVRSEDIAIEADSKLTERHQTTIPASIRDALHLRSGDRIHYTLLSTGEVLLSKYSEATEDGVMRSFLDFLSQDVANN
PQTLKKLDLSRGYELVDGIDVNLDDEISDED

Download         Length: 336 bp

>AT93695 NZ_CP026216:1833965-1834300 [Citrobacter sp. CFNIH10]
ATGTTCGCCTATGTTCGATCTGAAGACATTGCCATTGAAGCGGATTCTAAATTGACGGAACGACATCAAACGACTATCCC
TGCGTCGATCAGGGACGCTTTACATCTTCGCAGTGGTGATCGTATTCATTACACATTGCTTTCCACGGGTGAAGTACTGC
TTTCAAAATACAGTGAAGCAACGGAGGACGGTGTGATGCGATCATTCCTGGACTTCTTATCACAGGATGTGGCGAATAAC
CCACAAACGCTGAAGAAGCTGGATTTATCCCGTGGCTATGAACTGGTTGATGGTATCGACGTCAATCTTGATGATGAAAT
CAGCGACGAAGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S7D6F0

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q8DNJ3

References