Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 682525..683225 Replicon chromosome
Accession NZ_CP026115
Organism Pseudomonas putida strain W5

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag C2H86_RS03180 Protein ID WP_159411403.1
Coordinates 682929..683225 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag C2H86_RS03175 Protein ID WP_159411402.1
Coordinates 682525..682926 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2H86_RS03155 677644..678465 - 822 WP_159411400.1 transporter substrate-binding domain-containing protein -
C2H86_RS03160 678545..679489 - 945 WP_159411401.1 FAD-binding protein -
C2H86_RS03165 679490..680239 - 750 WP_014590265.1 electron transfer flavoprotein subunit beta/FixA family protein -
C2H86_RS03170 680771..682453 + 1683 WP_099814148.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
C2H86_RS03175 682525..682926 - 402 WP_159411402.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
C2H86_RS03180 682929..683225 - 297 WP_159411403.1 type II toxin-antitoxin system MqsR family toxin Toxin
C2H86_RS03185 683320..684645 - 1326 WP_159411404.1 MFS transporter -
C2H86_RS03190 684717..685196 - 480 WP_159411405.1 histidine kinase -
C2H86_RS03195 685367..685843 - 477 WP_159411406.1 sigma-70 family RNA polymerase sigma factor -
C2H86_RS03200 686048..687205 + 1158 WP_159411407.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Zinc finger, MqsA-type

(3-46)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11208.98 Da        Isoelectric Point: 8.8808

>T93337 WP_159411403.1 NZ_CP026115:c683225-682929 [Pseudomonas putida]
MEKRTPHCSLERVRALVSAGRISPTTASLRGAQALGVEYPEMLEIINGLERRDFHKSMTSYADHRIWQDVYRPLTAKGYL
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

>T93337 NZ_CP026115:c683225-682929 [Pseudomonas putida]
ATGGAAAAGAGAACGCCTCATTGCTCGCTGGAGCGGGTGAGAGCATTGGTCAGCGCTGGCCGCATCAGTCCGACGACTGC
TTCGTTGCGGGGCGCGCAGGCCCTGGGAGTGGAGTATCCGGAGATGCTTGAGATTATCAACGGTCTGGAGCGCAGAGACT
TCCACAAGAGCATGACCAGTTATGCCGACCACCGCATTTGGCAAGATGTCTACCGACCGCTTACAGCCAAGGGTTACTTG
TACCTGAAACTGTCGGTAGTGGATGACGTGCTAATCGTGTCTTTCAAGGAGTTGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14726.75 Da        Isoelectric Point: 4.7942

>AT93337 WP_159411402.1 NZ_CP026115:c682926-682525 [Pseudomonas putida]
MKCPICGGAELAPDILDMPYRYKGESTVIPDVSGDYCSACGEAVLSHGEALRVSELMSAFNRQVNAQDVDPDFITTVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTRPPVALIKLFKLLDRHPELFEEIRTA

Download         Length: 402 bp

>AT93337 NZ_CP026115:c682926-682525 [Pseudomonas putida]
ATGAAATGCCCAATTTGCGGCGGTGCGGAGCTTGCACCGGATATTCTGGACATGCCCTATCGCTACAAAGGGGAGTCAAC
AGTGATTCCTGATGTTTCAGGCGACTACTGCTCTGCCTGTGGCGAGGCAGTACTGAGTCATGGCGAGGCTTTGCGTGTCA
GTGAACTGATGTCTGCTTTTAATCGCCAGGTCAATGCTCAAGATGTTGACCCTGATTTCATTACTACCGTGCGCAAGAAA
TTTGATTTGGATCAGCGGGAGGCTGGTGAAATATTCGGTGGAGGAGTGAATGCTTTTTCACGATACGAAAACGGCAAGAC
CAGACCGCCAGTGGCGCTGATCAAATTGTTCAAGCTGCTCGACCGTCACCCGGAGTTGTTCGAAGAAATCAGGACAGCGT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References