Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2613404..2613683 Replicon chromosome
Accession NZ_CP026080
Organism Staphylococcus aureus strain FDAARGOS_12

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RK70_RS13420 Protein ID WP_001802298.1
Coordinates 2613404..2613508 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2613504..2613683 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK70_RS13395 2608788..2609570 + 783 WP_000908177.1 ABC transporter ATP-binding protein -
RK70_RS13400 2609638..2610495 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
RK70_RS13405 2611200..2611292 - 93 WP_001790138.1 hypothetical protein -
RK70_RS13410 2611581..2612717 + 1137 WP_000115562.1 SAP domain-containing protein -
RK70_RS14120 2612760..2613243 + 484 Protein_2479 recombinase family protein -
RK70_RS13420 2613404..2613508 + 105 WP_001802298.1 hypothetical protein Toxin
- 2613504..2613683 - 180 - - Antitoxin
RK70_RS13425 2613951..2615042 - 1092 WP_000495671.1 lytic regulatory protein -
RK70_RS13430 2615308..2616288 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
RK70_RS13435 2616290..2616610 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK70_RS13440 2616762..2617427 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T93239 WP_001802298.1 NZ_CP026080:2613404-2613508 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93239 NZ_CP026080:2613404-2613508 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT93239 NZ_CP026080:c2613683-2613504 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGCAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References