93218

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1481571..1481849 Replicon chromosome
Accession NZ_CP026079
Organism Staphylococcus aureus strain FDAARGOS_9

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RK67_RS07525 Protein ID WP_001802298.1
Coordinates 1481571..1481675 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1481671..1481849 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK67_RS07500 1478368..1479150 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
RK67_RS07505 1479218..1480075 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
RK67_RS07515 1480733..1480891 - 159 WP_001792784.1 hypothetical protein -
RK67_RS07525 1481571..1481675 + 105 WP_001802298.1 hypothetical protein Toxin
- 1481671..1481849 - 179 - - Antitoxin
RK67_RS07530 1482108..1482752 - 645 Protein_1401 transcriptional regulator -
RK67_RS07535 1482878..1483963 + 1086 WP_000868132.1 tyrosine-type recombinase/integrase -
RK67_RS07540 1483960..1485852 + 1893 WP_001557544.1 site-specific integrase -
RK67_RS07545 1485859..1486236 + 378 WP_000361059.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(8-48)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T93218 WP_001802298.1 NZ_CP026079:1481571-1481675 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93218 NZ_CP026079:1481571-1481675 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT93218 NZ_CP026079:c1481849-1481671 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References