Detailed information of TA system TA093209

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2535375..2535557
• Replicon: chromosome
• Accession: NZ_CP026077
• Organism: Staphylococcus aureus strain FDAARGOS_7

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK65_RS14115
• Protein ID: WP_001801861.1
• Coordinates: 2535375..2535470 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2535498..2535557 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK65_RS12835	2531035..2531661	+	627	WP_000669046.1	hypothetical protein	-
RK65_RS12840	2531702..2532046	+	345	WP_000627551.1	DUF3969 family protein	-
RK65_RS12845	2532144..2532695	+	552	WP_000414205.1	hypothetical protein	-
RK65_RS12850	2532913..2533554	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
RK65_RS12855	2533668..2533853	-	186	WP_000809857.1	hypothetical protein	-
RK65_RS12860	2533855..2534031	-	177	WP_000375476.1	hypothetical protein	-
RK65_RS12865	2534042..2534425	-	384	WP_000070812.1	hypothetical protein	-
RK65_RS12875	2535029..2535172	-	144	WP_001549059.1	transposase	-
RK65_RS14115	2535375..2535470	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2535498..2535557	-	60	-	-	Antitoxin
RK65_RS12885	2535593..2535694	+	102	WP_001791893.1	hypothetical protein	-
RK65_RS12890	2535672..2535848	-	177	Protein_2419	transposase	-
RK65_RS12895	2536042..2536419	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T93209 WP_001801861.1 NZ_CP026077:2535375-2535470 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T93209 NZ_CP026077:2535375-2535470 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT93209 NZ_CP026077:c2535557-2535498 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin