Detailed information of TA system TA093199

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2769426..2769608
• Replicon: chromosome
• Accession: NZ_CP026076
• Organism: Staphylococcus aureus strain FDAARGOS_4

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK63_RS14775
• Protein ID: WP_001801861.1
• Coordinates: 2769426..2769521 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2769549..2769608 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK63_RS14430	2765086..2765712	+	627	WP_000669046.1	hypothetical protein	-
RK63_RS14435	2765753..2766097	+	345	WP_000627551.1	DUF3969 family protein	-
RK63_RS14440	2766195..2766746	+	552	WP_000414205.1	hypothetical protein	-
RK63_RS14445	2766964..2767605	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
RK63_RS14450	2767719..2767904	-	186	WP_000809857.1	hypothetical protein	-
RK63_RS14455	2767906..2768082	-	177	WP_000375476.1	hypothetical protein	-
RK63_RS14460	2768093..2768476	-	384	WP_000070811.1	hypothetical protein	-
RK63_RS14470	2769080..2769223	-	144	WP_001549059.1	transposase	-
RK63_RS14775	2769426..2769521	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2769549..2769608	-	60	-	-	Antitoxin
RK63_RS14480	2769644..2769745	+	102	WP_001791893.1	hypothetical protein	-
RK63_RS14485	2769723..2769899	-	177	Protein_2693	transposase	-
RK63_RS14490	2770093..2770470	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T93199 WP_001801861.1 NZ_CP026076:2769426-2769521 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T93199 NZ_CP026076:2769426-2769521 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT93199 NZ_CP026076:c2769608-2769549 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin