Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 293169..293432 Replicon chromosome
Accession NZ_CP026076
Organism Staphylococcus aureus strain FDAARGOS_4

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RK63_RS01825 Protein ID WP_001802298.1
Coordinates 293328..293432 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 293169..293333 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK63_RS01805 289352..290017 - 666 WP_001024094.1 SDR family oxidoreductase -
RK63_RS01810 290169..290489 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK63_RS01815 290491..291471 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
RK63_RS01820 291737..292828 + 1092 WP_000495671.1 lytic regulatory protein -
- 293169..293333 + 165 - - Antitoxin
RK63_RS01825 293328..293432 - 105 WP_001802298.1 hypothetical protein Toxin
RK63_RS14745 293593..294076 - 484 Protein_312 recombinase family protein -
RK63_RS01835 294119..295255 - 1137 WP_000115564.1 SAP domain-containing protein -
RK63_RS01840 295544..295636 + 93 WP_001790138.1 hypothetical protein -
RK63_RS01845 296341..297198 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
RK63_RS01850 297266..298048 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T93192 WP_001802298.1 NZ_CP026076:c293432-293328 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93192 NZ_CP026076:c293432-293328 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT93192 NZ_CP026076:293169-293333 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References