Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 708560..708776 Replicon chromosome
Accession NZ_CP026074
Organism Staphylococcus aureus strain FDAARGOS_47

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RL05_RS04150 Protein ID WP_001802298.1
Coordinates 708672..708776 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 708560..708615 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RL05_RS04130 704766..705431 - 666 WP_001024092.1 SDR family oxidoreductase -
RL05_RS04135 705583..705903 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RL05_RS04140 705905..706882 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
RL05_RS04145 707148..708239 + 1092 WP_000495669.1 hypothetical protein -
- 708560..708615 + 56 - - Antitoxin
RL05_RS04150 708672..708776 - 105 WP_001802298.1 hypothetical protein Toxin
RL05_RS04160 709456..709614 + 159 WP_001792784.1 hypothetical protein -
RL05_RS04170 710272..711129 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
RL05_RS04175 711197..711979 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T93174 WP_001802298.1 NZ_CP026074:c708776-708672 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93174 NZ_CP026074:c708776-708672 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT93174 NZ_CP026074:708560-708615 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References