Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2715819..2716097 Replicon chromosome
Accession NZ_CP026073
Organism Staphylococcus aureus strain FDAARGOS_42

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RL00_RS14055 Protein ID WP_001802298.1
Coordinates 2715819..2715923 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2715919..2716097 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RL00_RS14030 2712615..2713397 + 783 WP_000908178.1 ABC transporter ATP-binding protein -
RL00_RS14035 2713465..2714322 + 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
RL00_RS14045 2714981..2715139 - 159 WP_001792784.1 hypothetical protein -
RL00_RS14055 2715819..2715923 + 105 WP_001802298.1 hypothetical protein Toxin
- 2715919..2716097 - 179 - - Antitoxin
RL00_RS14060 2716356..2717447 - 1092 WP_000495683.1 hypothetical protein -
RL00_RS14065 2717713..2718693 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
RL00_RS14070 2718695..2719015 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RL00_RS14075 2719167..2719832 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T93156 WP_001802298.1 NZ_CP026073:2715819-2715923 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93156 NZ_CP026073:2715819-2715923 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT93156 NZ_CP026073:c2716097-2715919 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References