Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 228890..229072 Replicon chromosome
Accession NZ_CP026073
Organism Staphylococcus aureus strain FDAARGOS_42

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RL00_RS14620 Protein ID WP_001801861.1
Coordinates 228977..229072 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 228890..228949 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RL00_RS01465 228028..228405 + 378 WP_001037045.1 DUF1433 domain-containing protein -
RL00_RS01470 228599..228775 + 177 Protein_236 transposase -
RL00_RS01475 228753..228854 - 102 WP_001791893.1 hypothetical protein -
- 228890..228949 + 60 - - Antitoxin
RL00_RS14620 228977..229072 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
RL00_RS01485 229275..229418 + 144 WP_001549059.1 transposase -
RL00_RS01495 230022..230405 + 384 WP_000070811.1 hypothetical protein -
RL00_RS01500 230416..230592 + 177 WP_000375477.1 hypothetical protein -
RL00_RS01510 230966..231523 + 558 Protein_242 ImmA/IrrE family metallo-endopeptidase -
RL00_RS01515 231721..232293 - 573 WP_000414202.1 hypothetical protein -
RL00_RS01520 232394..232735 - 342 WP_000627541.1 DUF3969 family protein -
RL00_RS01525 232776..233402 - 627 WP_000669017.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 210718..235960 25242


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T93143 WP_001801861.1 NZ_CP026073:c229072-228977 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T93143 NZ_CP026073:c229072-228977 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT93143 NZ_CP026073:228890-228949 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References