Detailed information of TA system TA093137

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2592406..2592588
• Replicon: chromosome
• Accession: NZ_CP026072
• Organism: Staphylococcus aureus strain FDAARGOS_35

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK93_RS15805
• Protein ID: WP_001801861.1
• Coordinates: 2592493..2592588 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2592406..2592465 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK93_RS13790	2591544..2591921	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
RK93_RS13795	2592115..2592291	+	177	Protein_2547	transposase	-
RK93_RS13800	2592269..2592370	-	102	WP_001791893.1	hypothetical protein	-
-	2592406..2592465	+	60	-	-	Antitoxin
RK93_RS15805	2592493..2592588	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
RK93_RS13810	2592791..2592934	+	144	WP_001549059.1	transposase	-
RK93_RS13820	2593538..2593921	+	384	WP_000070811.1	hypothetical protein	-
RK93_RS13825	2593932..2594108	+	177	WP_000375476.1	hypothetical protein	-
RK93_RS13830	2594110..2594295	+	186	WP_000809857.1	hypothetical protein	-
RK93_RS13835	2594409..2595050	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
RK93_RS13840	2595268..2595819	-	552	WP_000414205.1	hypothetical protein	-
RK93_RS13845	2595917..2596261	-	345	WP_000627551.1	DUF3969 family protein	-
RK93_RS13850	2596302..2596928	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2573886..2618613	44727

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T93137 WP_001801861.1 NZ_CP026072:c2592588-2592493 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T93137 NZ_CP026072:c2592588-2592493 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT93137 NZ_CP026072:2592406-2592465 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin