Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | SprA2-SprA2AS/- |
Location | 1963190..1963374 | Replicon | chromosome |
Accession | NZ_CP026072 | ||
Organism | Staphylococcus aureus strain FDAARGOS_35 |
Toxin (Protein)
Gene name | SprA2 | Uniprot ID | Q2FVI9 |
Locus tag | RK93_RS10060 | Protein ID | WP_000482650.1 |
Coordinates | 1963190..1963297 (+) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | SprA2AS | ||
Locus tag | - | ||
Coordinates | 1963314..1963374 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RK93_RS10035 | 1958552..1959025 | + | 474 | WP_000456489.1 | GyrI-like domain-containing protein | - |
RK93_RS10040 | 1959148..1960359 | - | 1212 | WP_001192075.1 | multidrug effflux MFS transporter | - |
RK93_RS10045 | 1960541..1961200 | - | 660 | WP_000831298.1 | membrane protein | - |
RK93_RS10050 | 1961260..1962402 | - | 1143 | WP_001176863.1 | glycerate kinase | - |
RK93_RS10055 | 1962670..1963056 | + | 387 | WP_000779358.1 | flippase GtxA | - |
RK93_RS10060 | 1963190..1963297 | + | 108 | WP_000482650.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
- | 1963314..1963374 | - | 61 | - | - | Antitoxin |
RK93_RS10070 | 1963925..1965688 | + | 1764 | WP_001064838.1 | ABC transporter ATP-binding protein/permease | - |
RK93_RS10075 | 1965713..1967446 | + | 1734 | WP_000486494.1 | ABC transporter ATP-binding protein/permease | - |
RK93_RS10085 | 1967677..1967844 | + | 168 | WP_001789936.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4011.78 Da Isoelectric Point: 11.0582
>T93124 WP_000482650.1 NZ_CP026072:1963190-1963297 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK
Download Length: 108 bp
>T93124 NZ_CP026072:1963190-1963297 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
Antitoxin
Download Length: 61 bp
>AT93124 NZ_CP026072:c1963374-1963314 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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