Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 2849089..2849351 Replicon chromosome
Accession NZ_CP026071
Organism Staphylococcus aureus strain FDAARGOS_30

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag RK88_RS14725 Protein ID WP_073392962.1
Coordinates 2849089..2849193 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2849188..2849351 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK88_RS14700 2845885..2846667 + 783 WP_000908186.1 ABC transporter ATP-binding protein -
RK88_RS14705 2846735..2847592 + 858 WP_042904853.1 Cof-type HAD-IIB family hydrolase -
RK88_RS14715 2848251..2848409 - 159 WP_001792784.1 hypothetical protein -
RK88_RS14725 2849089..2849193 + 105 WP_073392962.1 hypothetical protein Toxin
- 2849188..2849351 - 164 - - Antitoxin
RK88_RS14730 2849619..2851265 - 1647 WP_000277709.1 IS1182-like element ISSau3 family transposase -
RK88_RS14735 2851553..2852644 - 1092 WP_000495684.1 hypothetical protein -
RK88_RS14740 2852910..2853890 - 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
RK88_RS14745 2853892..2854212 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2849619..2851265 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T93115 WP_073392962.1 NZ_CP026071:2849089-2849193 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93115 NZ_CP026071:2849089-2849193 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT93115 NZ_CP026071:c2849351-2849188 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References