Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2558969..2559153 Replicon chromosome
Accession NZ_CP026071
Organism Staphylococcus aureus strain FDAARGOS_30

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag RK88_RS13145 Protein ID WP_000482647.1
Coordinates 2558969..2559076 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2559093..2559153 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK88_RS13120 2554331..2554804 + 474 WP_000456496.1 GyrI-like domain-containing protein -
RK88_RS13125 2554927..2556138 - 1212 WP_001191919.1 multidrug effflux MFS transporter -
RK88_RS13130 2556320..2556979 - 660 WP_000831298.1 membrane protein -
RK88_RS13135 2557039..2558181 - 1143 WP_001176855.1 glycerate kinase -
RK88_RS13140 2558449..2558835 + 387 WP_000779351.1 flippase GtxA -
RK88_RS13145 2558969..2559076 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2559093..2559153 - 61 - - Antitoxin
RK88_RS13155 2559724..2561487 + 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
RK88_RS13160 2561512..2563245 + 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
RK88_RS13170 2563476..2563643 + 168 Protein_2458 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T93112 WP_000482647.1 NZ_CP026071:2558969-2559076 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T93112 NZ_CP026071:2558969-2559076 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT93112 NZ_CP026071:c2559153-2559093 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References