Detailed information of TA system TA093103

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1209728..1209925
• Replicon: chromosome
• Accession: NZ_CP026071
• Organism: Staphylococcus aureus strain FDAARGOS_30

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: RK88_RS06395
• Protein ID: WP_000623369.1
• Coordinates: 1209818..1209925 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1209728..1209765 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK88_RS06360	1204921..1205208	-	288	WP_000410718.1	hypothetical protein	-
RK88_RS06365	1205549..1205839	+	291	WP_001791476.1	hypothetical protein	-
RK88_RS06370	1205927..1206568	-	642	Protein_1174	ABC transporter ATP-binding protein	-
RK88_RS06375	1206565..1206885	-	321	WP_000873929.1	YxeA family protein	-
RK88_RS06380	1206888..1208852	-	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
RK88_RS06385	1208896..1209168	-	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
RK88_RS06390	1209178..1209279	-	102	WP_001790623.1	hypothetical protein	-
-	1209728..1209765	+	38	-	-	Antitoxin
RK88_RS06395	1209818..1209925	-	108	WP_000623369.1	putative holin-like toxin	Toxin
RK88_RS06400	1210196..1210798	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
RK88_RS06405	1210813..1210989	-	177	WP_000214898.1	YkvS family protein	-
RK88_RS06410	1211188..1212174	+	987	WP_000668820.1	lipoate--protein ligase	-
RK88_RS06415	1212255..1212473	-	219	WP_000876825.1	IDEAL domain-containing protein	-
RK88_RS06420	1212683..1213252	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T93103 WP_000623369.1 NZ_CP026071:c1209925-1209818 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T93103 NZ_CP026071:c1209925-1209818 [Staphylococcus aureus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 38 bp

>AT93103 NZ_CP026071:1209728-1209765 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin