Detailed information of TA system TA093101

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 337190..337370
• Replicon: chromosome
• Accession: NZ_CP026071
• Organism: Staphylococcus aureus strain FDAARGOS_30

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK88_RS14780
• Protein ID: WP_001801861.1
• Coordinates: 337275..337370 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	337190..337247 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK88_RS02085	332603..335023	-	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-
RK88_RS02090	335548..335990	+	443	Protein_355	DUF1433 domain-containing protein	-
RK88_RS02095	335990..336433	+	444	WP_000731421.1	DUF1433 domain-containing protein	-
RK88_RS02100	336433..336876	+	444	WP_001037039.1	DUF1433 domain-containing protein	-
RK88_RS02105	337051..337152	-	102	WP_001791232.1	hypothetical protein	-
-	337190..337247	+	58	-	-	Antitoxin
RK88_RS14780	337275..337370	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
RK88_RS02115	337821..338267	+	447	WP_000747804.1	DUF1433 domain-containing protein	-
RK88_RS02120	338460..339029	+	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
RK88_RS02125	339029..340396	+	1368	WP_001093574.1	FRG domain-containing protein	-
RK88_RS02130	340545..341117	-	573	WP_000414222.1	hypothetical protein	-
RK88_RS02135	341215..341559	-	345	WP_000627550.1	DUF3969 family protein	-
RK88_RS02140	341600..342226	-	627	WP_000669038.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hysA	307428..344786	37358

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T93101 WP_001801861.1 NZ_CP026071:c337370-337275 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T93101 NZ_CP026071:c337370-337275 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT93101 NZ_CP026071:337190-337247 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin