Detailed information of TA system TA093092

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1980511..1980693
• Replicon: chromosome
• Accession: NZ_CP026070
• Organism: Staphylococcus aureus strain FDAARGOS_27

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK85_RS14315
• Protein ID: WP_001801861.1
• Coordinates: 1980598..1980693 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1980511..1980570 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK85_RS10520	1979649..1980026	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
RK85_RS10525	1980220..1980396	+	177	Protein_1926	transposase	-
RK85_RS10530	1980374..1980475	-	102	WP_001791893.1	hypothetical protein	-
-	1980511..1980570	+	60	-	-	Antitoxin
RK85_RS14315	1980598..1980693	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
RK85_RS10540	1980896..1981039	+	144	WP_001549059.1	transposase	-
RK85_RS10550	1981643..1982026	+	384	WP_000070812.1	hypothetical protein	-
RK85_RS10555	1982037..1982213	+	177	WP_000375476.1	hypothetical protein	-
RK85_RS10560	1982215..1982400	+	186	WP_000809857.1	hypothetical protein	-
RK85_RS10565	1982514..1983155	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
RK85_RS10570	1983373..1983924	-	552	WP_000414205.1	hypothetical protein	-
RK85_RS10575	1984022..1984366	-	345	WP_000627551.1	DUF3969 family protein	-
RK85_RS10580	1984407..1985033	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-129)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T93092 WP_001801861.1 NZ_CP026070:c1980693-1980598 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T93092 NZ_CP026070:c1980693-1980598 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT93092 NZ_CP026070:1980511-1980570 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin