Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1644903..1645182 Replicon chromosome
Accession NZ_CP026070
Organism Staphylococcus aureus strain FDAARGOS_27

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RK85_RS08420 Protein ID WP_001802298.1
Coordinates 1644903..1645007 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1645003..1645182 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK85_RS08395 1640287..1641069 + 783 WP_000908177.1 ABC transporter ATP-binding protein -
RK85_RS08400 1641137..1641994 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
RK85_RS08405 1642699..1642791 - 93 WP_001790138.1 hypothetical protein -
RK85_RS08410 1643080..1644216 + 1137 WP_000115562.1 SAP domain-containing protein -
RK85_RS14310 1644259..1644742 + 484 Protein_1574 recombinase family protein -
RK85_RS08420 1644903..1645007 + 105 WP_001802298.1 hypothetical protein Toxin
- 1645003..1645182 - 180 - - Antitoxin
RK85_RS08425 1645450..1646541 - 1092 WP_000495671.1 lytic regulatory protein -
RK85_RS08430 1646807..1647787 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
RK85_RS08435 1647789..1648109 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK85_RS08440 1648261..1648926 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T93083 WP_001802298.1 NZ_CP026070:1644903-1645007 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93083 NZ_CP026070:1644903-1645007 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT93083 NZ_CP026070:c1645182-1645003 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGCAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References