93075

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2811003..2811219 Replicon chromosome
Accession NZ_CP026069
Organism Staphylococcus aureus strain FDAARGOS_25

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RK83_RS14730 Protein ID WP_001802298.1
Coordinates 2811115..2811219 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2811003..2811058 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK83_RS14710 2807209..2807874 - 666 WP_001024095.1 SDR family oxidoreductase -
RK83_RS14715 2808026..2808346 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK83_RS14720 2808348..2809325 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
RK83_RS14725 2809591..2810682 + 1092 WP_000495669.1 hypothetical protein -
- 2811003..2811058 + 56 - - Antitoxin
RK83_RS14730 2811115..2811219 - 105 WP_001802298.1 hypothetical protein Toxin
RK83_RS14740 2811899..2812057 + 159 WP_001792784.1 hypothetical protein -
RK83_RS14750 2812715..2813572 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
RK83_RS14755 2813640..2814422 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T93075 WP_001802298.1 NZ_CP026069:c2811219-2811115 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93075 NZ_CP026069:c2811219-2811115 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT93075 NZ_CP026069:2811003-2811058 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9


Antitoxin

Download structure file

References