Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 2811003..2811219 | Replicon | chromosome |
Accession | NZ_CP026069 | ||
Organism | Staphylococcus aureus strain FDAARGOS_25 |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | Q2FWA7 |
Locus tag | RK83_RS14730 | Protein ID | WP_001802298.1 |
Coordinates | 2811115..2811219 (-) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF1 | ||
Locus tag | - | ||
Coordinates | 2811003..2811058 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RK83_RS14710 | 2807209..2807874 | - | 666 | WP_001024095.1 | SDR family oxidoreductase | - |
RK83_RS14715 | 2808026..2808346 | + | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
RK83_RS14720 | 2808348..2809325 | + | 978 | WP_000019734.1 | CDF family zinc efflux transporter CzrB | - |
RK83_RS14725 | 2809591..2810682 | + | 1092 | WP_000495669.1 | hypothetical protein | - |
- | 2811003..2811058 | + | 56 | - | - | Antitoxin |
RK83_RS14730 | 2811115..2811219 | - | 105 | WP_001802298.1 | hypothetical protein | Toxin |
RK83_RS14740 | 2811899..2812057 | + | 159 | WP_001792784.1 | hypothetical protein | - |
RK83_RS14750 | 2812715..2813572 | - | 858 | WP_000370925.1 | Cof-type HAD-IIB family hydrolase | - |
RK83_RS14755 | 2813640..2814422 | - | 783 | WP_000908182.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T93075 WP_001802298.1 NZ_CP026069:c2811219-2811115 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T93075 NZ_CP026069:c2811219-2811115 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
Antitoxin
Download Length: 56 bp
>AT93075 NZ_CP026069:2811003-2811058 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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