Detailed information of TA system TA093069

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1617348..1617528
• Replicon: chromosome
• Accession: NZ_CP026069
• Organism: Staphylococcus aureus strain FDAARGOS_25

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK83_RS15080
• Protein ID: WP_001801861.1
• Coordinates: 1617433..1617528 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1617348..1617405 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK83_RS08550	1613057..1613191	+	135	WP_001791797.1	hypothetical protein	-
RK83_RS08555	1613355..1614911	+	1557	WP_000028669.1	type I restriction-modification system subunit M	-
RK83_RS08560	1614904..1616133	+	1230	WP_000072626.1	restriction endonuclease subunit S	-
RK83_RS08565	1616585..1617079	+	495	Protein_1564	transposase	-
RK83_RS08570	1617070..1617231	+	162	Protein_1565	transposase	-
RK83_RS08575	1617209..1617310	-	102	WP_001792025.1	hypothetical protein	-
-	1617348..1617405	+	58	-	-	Antitoxin
RK83_RS15080	1617433..1617528	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
RK83_RS08580	1617673..1618685	+	1013	Protein_1568	IS3 family transposase	-
RK83_RS08585	1618883..1619455	-	573	WP_000414216.1	hypothetical protein	-
RK83_RS08590	1619556..1619897	-	342	WP_000627540.1	DUF3969 family protein	-
RK83_RS08595	1619938..1620564	-	627	WP_000669024.1	hypothetical protein	-
RK83_RS08600	1620639..1621634	-	996	WP_000070642.1	DUF4352 domain-containing protein	-
RK83_RS08605	1621715..1622365	-	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hlgA / lukD	1590516..1641546	51030

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T93069 WP_001801861.1 NZ_CP026069:c1617528-1617433 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T93069 NZ_CP026069:c1617528-1617433 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT93069 NZ_CP026069:1617348-1617405 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin