Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1879174..1879358 Replicon chromosome
Accession NZ_CP026068
Organism Staphylococcus aureus strain FDAARGOS_24

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag RK82_RS09830 Protein ID WP_000482650.1
Coordinates 1879251..1879358 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1879174..1879234 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK82_RS09805 1874704..1874871 - 168 WP_001790576.1 hypothetical protein -
RK82_RS09815 1875102..1876835 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
RK82_RS09820 1876860..1878623 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 1879174..1879234 + 61 - - Antitoxin
RK82_RS09830 1879251..1879358 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
RK82_RS09835 1879492..1879878 - 387 WP_000779358.1 flippase GtxA -
RK82_RS09840 1880146..1881288 + 1143 WP_001176863.1 glycerate kinase -
RK82_RS09845 1881348..1882007 + 660 WP_000831298.1 membrane protein -
RK82_RS09850 1882189..1883400 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
RK82_RS09855 1883523..1883996 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T93057 WP_000482650.1 NZ_CP026068:c1879358-1879251 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T93057 NZ_CP026068:c1879358-1879251 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT93057 NZ_CP026068:1879174-1879234 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References