Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1295986..1296168 Replicon chromosome
Accession NZ_CP026068
Organism Staphylococcus aureus strain FDAARGOS_24

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RK82_RS13915 Protein ID WP_001801861.1
Coordinates 1295986..1296081 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1296109..1296168 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK82_RS06450 1291646..1292272 + 627 WP_000669046.1 hypothetical protein -
RK82_RS06455 1292313..1292657 + 345 WP_000627551.1 DUF3969 family protein -
RK82_RS06460 1292755..1293306 + 552 WP_000414205.1 hypothetical protein -
RK82_RS06465 1293524..1294165 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
RK82_RS06470 1294279..1294464 - 186 WP_000809857.1 hypothetical protein -
RK82_RS06475 1294466..1294642 - 177 WP_000375476.1 hypothetical protein -
RK82_RS06480 1294653..1295036 - 384 WP_000070812.1 hypothetical protein -
RK82_RS06490 1295640..1295783 - 144 WP_001549059.1 transposase -
RK82_RS13915 1295986..1296081 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1296109..1296168 - 60 - - Antitoxin
RK82_RS06500 1296204..1296305 + 102 WP_001791893.1 hypothetical protein -
RK82_RS06505 1296283..1296459 - 177 Protein_1233 transposase -
RK82_RS06510 1296653..1297030 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1269959..1348500 78541


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T93050 WP_001801861.1 NZ_CP026068:1295986-1296081 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T93050 NZ_CP026068:1295986-1296081 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT93050 NZ_CP026068:c1296168-1296109 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References