Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2778179..2778396 Replicon chromosome
Accession NZ_CP026067
Organism Staphylococcus aureus strain FDAARGOS_21

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RK79_RS14420 Protein ID WP_001802298.1
Coordinates 2778292..2778396 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2778179..2778234 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK79_RS14400 2774310..2774975 - 666 WP_001024091.1 SDR family oxidoreductase -
RK79_RS14405 2775127..2775447 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK79_RS14410 2775449..2776429 + 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
RK79_RS14415 2776695..2777786 + 1092 WP_047213685.1 hypothetical protein -
- 2778179..2778234 + 56 - - Antitoxin
RK79_RS14420 2778292..2778396 - 105 WP_001802298.1 hypothetical protein Toxin
RK79_RS15025 2778557..2779054 - 498 Protein_2677 recombinase family protein -
RK79_RS14430 2779104..2780231 - 1128 WP_047213687.1 SAP domain-containing protein -
RK79_RS14435 2781280..2782137 - 858 WP_000370936.1 Cof-type HAD-IIB family hydrolase -
RK79_RS14440 2782205..2782987 - 783 WP_000908193.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T93048 WP_001802298.1 NZ_CP026067:c2778396-2778292 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93048 NZ_CP026067:c2778396-2778292 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT93048 NZ_CP026067:2778179-2778234 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References