Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2796913..2797129 Replicon chromosome
Accession NZ_CP026066
Organism Staphylococcus aureus strain FDAARGOS_20

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag RK78_RS14310 Protein ID WP_073392962.1
Coordinates 2797025..2797129 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2796913..2796968 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK78_RS14290 2793107..2793772 - 666 WP_001024099.1 SDR family oxidoreductase -
RK78_RS14295 2793924..2794244 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK78_RS14300 2794246..2795226 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
RK78_RS14305 2795492..2796583 + 1092 WP_000495684.1 hypothetical protein -
- 2796913..2796968 + 56 - - Antitoxin
RK78_RS14310 2797025..2797129 - 105 WP_073392962.1 hypothetical protein Toxin
RK78_RS14320 2797809..2797967 + 159 WP_001792784.1 hypothetical protein -
RK78_RS14330 2798626..2799483 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
RK78_RS14335 2799551..2800333 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T93030 WP_073392962.1 NZ_CP026066:c2797129-2797025 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T93030 NZ_CP026066:c2797129-2797025 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT93030 NZ_CP026066:2796913-2796968 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References