Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 263681..263865 Replicon chromosome
Accession NZ_CP026066
Organism Staphylococcus aureus strain FDAARGOS_20

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag RK78_RS01495 Protein ID WP_000482647.1
Coordinates 263758..263865 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 263681..263741 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK78_RS01470 259191..259358 - 168 Protein_275 hypothetical protein -
RK78_RS01480 259589..261322 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
RK78_RS01485 261347..263110 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 263681..263741 + 61 - - Antitoxin
RK78_RS01495 263758..263865 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
RK78_RS01500 263999..264385 - 387 WP_000779351.1 flippase GtxA -
RK78_RS01505 264653..265795 + 1143 WP_001176857.1 glycerate kinase -
RK78_RS01510 265855..266514 + 660 WP_000831298.1 membrane protein -
RK78_RS01515 266696..267907 + 1212 WP_001191920.1 multidrug effflux MFS transporter -
RK78_RS01520 268030..268503 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T93013 WP_000482647.1 NZ_CP026066:c263865-263758 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T93013 NZ_CP026066:c263865-263758 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT93013 NZ_CP026066:263681-263741 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References