Detailed information of TA system TA093004

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2393843..2394023
• Replicon: chromosome
• Accession: NZ_CP026064
• Organism: Staphylococcus aureus strain FDAARGOS_19

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK77_RS14915
• Protein ID: WP_001801861.1
• Coordinates: 2393928..2394023 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2393843..2393900 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK77_RS12325	2388867..2390048	+	1182	WP_000162901.1	hypothetical protein	-
RK77_RS12330	2390365..2390664	-	300	WP_000095392.1	WXG100 family type VII secretion target	-
RK77_RS12335	2390679..2392292	-	1614	WP_000926708.1	lipase	-
RK77_RS12340	2392337..2392777	+	441	WP_000759947.1	DUF1433 domain-containing protein	-
RK77_RS12345	2392983..2393360	+	378	WP_001036002.1	DUF1433 domain-containing protein	-
RK77_RS12350	2393554..2393726	+	173	Protein_2291	transposase	-
RK77_RS12355	2393704..2393805	-	102	WP_001791232.1	hypothetical protein	-
-	2393843..2393900	+	58	-	-	Antitoxin
RK77_RS14915	2393928..2394023	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
RK77_RS12360	2394168..2394272	+	105	WP_001670380.1	transposase	-
RK77_RS15030	2394446..2394670	+	225	WP_001805677.1	IS3 family transposase	-
RK77_RS12370	2394852..2395235	+	384	WP_000070809.1	hypothetical protein	-
RK77_RS12375	2395246..2395422	+	177	WP_000375476.1	hypothetical protein	-
RK77_RS12385	2395795..2396364	+	570	WP_000864144.1	ImmA/IrrE family metallo-endopeptidase	-
RK77_RS12390	2396561..2397133	-	573	WP_000414208.1	hypothetical protein	-
RK77_RS12395	2397234..2397575	-	342	WP_000627536.1	DUF3969 family protein	-
RK77_RS12400	2397616..2398242	-	627	WP_000669029.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	2377613..2421171	43558

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T93004 WP_001801861.1 NZ_CP026064:c2394023-2393928 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T93004 NZ_CP026064:c2394023-2393928 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT93004 NZ_CP026064:2393843-2393900 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin