Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2062448..2062727 Replicon chromosome
Accession NZ_CP026064
Organism Staphylococcus aureus strain FDAARGOS_19

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag RK77_RS10305 Protein ID WP_075583739.1
Coordinates 2062448..2062552 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2062548..2062727 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK77_RS10275 2059246..2060028 + 783 WP_000908181.1 ABC transporter ATP-binding protein -
RK77_RS10280 2060096..2060953 + 858 WP_000370944.1 Cof-type HAD-IIB family hydrolase -
RK77_RS10290 2061613..2061771 - 159 WP_024928151.1 hypothetical protein -
RK77_RS10300 2062189..2062350 + 162 Protein_1941 helix-turn-helix domain-containing protein -
RK77_RS10305 2062448..2062552 + 105 WP_075583739.1 hypothetical protein Toxin
- 2062548..2062727 - 180 - - Antitoxin
RK77_RS10310 2063067..2064158 - 1092 WP_000495678.1 hypothetical protein -
RK77_RS10315 2064424..2065404 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
RK77_RS10320 2065406..2065726 - 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RK77_RS10325 2065878..2066543 + 666 WP_001024097.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T92995 WP_075583739.1 NZ_CP026064:2062448-2062552 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

>T92995 NZ_CP026064:2062448-2062552 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTAATCAAGGCCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT92995 NZ_CP026064:c2062727-2062548 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGTAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCAG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References