Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1775652..1775836 Replicon chromosome
Accession NZ_CP026064
Organism Staphylococcus aureus strain FDAARGOS_19

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag RK77_RS08745 Protein ID WP_000482647.1
Coordinates 1775652..1775759 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1775776..1775836 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK77_RS08720 1771017..1771490 + 474 WP_000456498.1 GyrI-like domain-containing protein -
RK77_RS08725 1771613..1772824 - 1212 WP_001191976.1 multidrug effflux MFS transporter -
RK77_RS08730 1773003..1773662 - 660 WP_000831298.1 membrane protein -
RK77_RS08735 1773722..1774864 - 1143 WP_001176863.1 glycerate kinase -
RK77_RS08740 1775132..1775518 + 387 WP_000779356.1 flippase GtxA -
RK77_RS08745 1775652..1775759 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1775776..1775836 - 61 - - Antitoxin
RK77_RS08750 1776463..1778226 + 1764 WP_001064811.1 ABC transporter ATP-binding protein/permease -
RK77_RS08755 1778251..1779984 + 1734 WP_000486501.1 ABC transporter ATP-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T92991 WP_000482647.1 NZ_CP026064:1775652-1775759 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T92991 NZ_CP026064:1775652-1775759 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT92991 NZ_CP026064:c1775836-1775776 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References