Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3698004..3698226 Replicon chromosome
Accession NZ_CP026028
Organism Escherichia coli strain CIT

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag C2H83_RS19215 Protein ID WP_000141634.1
Coordinates 3698004..3698111 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3698160..3698226 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2H83_RS19190 3693257..3694009 - 753 Protein_3511 cellulose biosynthesis protein BcsQ -
C2H83_RS19195 3694021..3694209 - 189 WP_001063318.1 YhjR family protein -
C2H83_RS19200 3694482..3696053 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
C2H83_RS19205 3696050..3696241 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
C2H83_RS19210 3696238..3697917 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
C2H83_RS19215 3698004..3698111 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3698160..3698226 + 67 - - Antitoxin
C2H83_RS19230 3698587..3699858 + 1272 WP_001295225.1 transporter -
C2H83_RS19235 3699888..3700892 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
C2H83_RS19240 3700889..3701872 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
C2H83_RS19245 3701883..3702785 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T92864 WP_000141634.1 NZ_CP026028:c3698111-3698004 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T92864 NZ_CP026028:c3698111-3698004 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT92864 NZ_CP026028:3698160-3698226 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References