Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 317625..318277 Replicon plasmid p-unname2
Accession NZ_CP025986
Organism Ralstonia solanacearum strain RSCM

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CYD94_RS19085 Protein ID WP_103025913.1
Coordinates 317625..317969 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CYD94_RS19090 Protein ID WP_020425351.1
Coordinates 317966..318277 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYD94_RS19070 313321..314484 - 1164 WP_011003438.1 2-methylcitrate synthase -
CYD94_RS19075 314536..315432 - 897 WP_038962849.1 methylisocitrate lyase -
CYD94_RS19080 315625..317574 + 1950 WP_058907710.1 propionate catabolism operon regulatory protein PrpR -
CYD94_RS19085 317625..317969 + 345 WP_103025913.1 toxin Toxin
CYD94_RS19090 317966..318277 + 312 WP_020425351.1 transcriptional regulator Antitoxin
CYD94_RS19095 318417..319226 - 810 WP_043885575.1 DUF2242 domain-containing protein -
CYD94_RS19105 320471..322309 + 1839 WP_071615383.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - flgC / flgG / fliM / fliG / fliI / icl / htpB / acrB / adeG / cheY / cheB / cheW / motA / cyaB 1..2212170 2212170


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-91)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13213.91 Da        Isoelectric Point: 8.4489

>T92634 WP_103025913.1 NZ_CP025986:317625-317969 [Ralstonia solanacearum]
MDATFIELPPFQRLREHYLSDDEYRALQQELLARPDAGDVIKGTGGLRKLRFSDKRRGKGKRGGLRVIDYHWDGGGQFWM
FVVYDKGEADDLSSDERKVLARLLEQDVKARSER

Download         Length: 345 bp

>T92634 NZ_CP025986:317625-317969 [Ralstonia solanacearum]
ATGGATGCTACCTTTATCGAGTTGCCGCCTTTTCAGAGGCTGCGGGAGCACTATCTCTCGGACGACGAGTACCGAGCGCT
CCAACAGGAACTGCTGGCCCGGCCGGACGCCGGCGACGTCATCAAGGGGACAGGTGGCCTACGCAAGCTGCGATTTTCGG
ACAAGCGGCGCGGCAAAGGTAAGCGCGGCGGTCTGCGCGTGATTGACTACCACTGGGATGGAGGCGGCCAATTCTGGATG
TTTGTCGTCTACGACAAGGGCGAGGCGGACGACCTTTCCAGCGACGAGCGCAAAGTGCTGGCACGGCTGTTGGAGCAGGA
CGTCAAGGCAAGGAGTGAGCGATGA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11619.65 Da        Isoelectric Point: 10.7132

>AT92634 WP_020425351.1 NZ_CP025986:317966-318277 [Ralstonia solanacearum]
MKRNLFAELKEGMDALAAEREGKMTLRKVKVRVLQPLDVTAEEIKAVRAAAHASQAVMARRLRVNVRTYQNWEQGTAKPN
TQAAVLIKLVEKHPETLQMLEAL

Download         Length: 312 bp

>AT92634 NZ_CP025986:317966-318277 [Ralstonia solanacearum]
ATGAAACGGAACCTGTTTGCTGAGTTGAAGGAGGGGATGGATGCGCTTGCCGCAGAGCGCGAAGGAAAGATGACCCTTCG
CAAGGTGAAGGTCCGCGTGCTCCAGCCGCTTGACGTGACAGCCGAAGAAATCAAGGCCGTTCGCGCAGCGGCACATGCTT
CACAGGCTGTCATGGCACGTCGACTGCGCGTCAATGTGCGCACCTACCAGAACTGGGAACAAGGAACCGCCAAACCGAAC
ACCCAGGCGGCTGTGTTGATCAAGCTCGTCGAGAAGCATCCGGAAACGTTGCAGATGCTGGAAGCGCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References