Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 37055..37557 Replicon plasmid pEM148
Accession NZ_CP025980
Organism Escherichia marmotae strain HT073016

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag C1192_RS24075 Protein ID WP_038355928.1
Coordinates 37303..37557 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C1192_RS24070 Protein ID WP_038355929.1
Coordinates 37055..37306 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1192_RS24055 33328..33882 + 555 Protein_36 ISNCY family transposase -
C1192_RS24060 34064..34291 + 228 Protein_37 helix-turn-helix domain-containing protein -
C1192_RS24065 34478..36424 - 1947 WP_052463078.1 DUF4116 domain-containing protein -
C1192_RS24070 37055..37306 + 252 WP_038355929.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
C1192_RS24075 37303..37557 + 255 WP_038355928.1 type II toxin-antitoxin system mRNA interferase toxin YoeB Toxin
C1192_RS24080 37586..37843 - 258 WP_052463077.1 hypothetical protein -
C1192_RS24085 38373..38909 - 537 WP_038355927.1 type II secretion system protein M -
C1192_RS24090 38896..40089 - 1194 WP_038355926.1 type II secretion system protein GspL -
C1192_RS24095 40086..41063 - 978 WP_038355925.1 type II secretion system minor pseudopilin GspK -
C1192_RS24100 41063..41665 - 603 WP_038355924.1 type II secretion system minor pseudopilin GspJ -
C1192_RS24105 41662..42033 - 372 WP_038355923.1 type II secretion system minor pseudopilin GspI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - nleB1 / gspM / gspK / gspJ / gspI / gspH / gspG / gspF / gspE / gspD / gspC / spa40 / spa29 / spa9 / spa24 / spa47 / spa15 / mxiA / mxiC / mxiD / mxiJ / mxiH / ipgF / ipgC / ipaB / yopJ/yopP / efa1 / cif / papD / papC / papH 1..148809 148809


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10191.60 Da        Isoelectric Point: 8.0353

>T92627 WP_038355928.1 NZ_CP025980:37303-37557 [Escherichia marmotae]
VKLTWSEEAWDDYLYWQETDKRMVKKINELIKDTRRTPFEGKGKPEPLKHNLSGFWSRRITEEHRLVYAVTDDSMLIAAC
RYHY

Download         Length: 255 bp

>T92627 NZ_CP025980:37303-37557 [Escherichia marmotae]
GTGAAACTAACCTGGTCTGAGGAAGCGTGGGACGATTATCTGTATTGGCAGGAGACGGATAAGCGCATGGTTAAAAAGAT
CAATGAACTAATCAAGGACACCCGTAGAACTCCGTTTGAAGGTAAAGGAAAACCAGAGCCCTTAAAGCATAATCTCTCGG
GCTTTTGGTCCCGACGAATTACAGAAGAGCACCGGCTGGTATATGCAGTCACTGACGATTCAATGCTAATTGCGGCATGC
CGTTACCACTATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9368.57 Da        Isoelectric Point: 4.5843

>AT92627 WP_038355929.1 NZ_CP025980:37055-37306 [Escherichia marmotae]
MRTISYSEARQNLSSTMLRAVEDNAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPTNARRLMDSIDSLKSGRGTEKD
IIE

Download         Length: 252 bp

>AT92627 NZ_CP025980:37055-37306 [Escherichia marmotae]
ATGCGTACCATCAGCTATAGCGAAGCACGCCAGAATTTATCTTCAACGATGCTGAGAGCTGTTGAAGATAACGCCCCAAT
TCTGATCACTCGTCAGAACGGAGAGGCTTGTGTTCTTATGTCGCTCGAAGAATATAACTCCCTCGAAGAAACTGCGTATC
TTCTGCGATCCCCTACTAACGCCCGGAGGTTGATGGATTCAATCGATAGTCTAAAATCAGGAAGAGGCACGGAAAAGGAT
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References