Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 3566968..3567662 Replicon chromosome
Accession NZ_CP025799
Organism Dickeya zeae strain MS2

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag C1O30_RS16145 Protein ID WP_102802202.1
Coordinates 3566968..3567372 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag C1O30_RS16150 Protein ID WP_102802203.1
Coordinates 3567369..3567662 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1O30_RS16130 3563717..3564481 + 765 WP_012885864.1 SDR family oxidoreductase -
C1O30_RS16135 3564508..3565395 + 888 WP_199770298.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
C1O30_RS16140 3565410..3566618 - 1209 WP_199770299.1 MFS transporter -
C1O30_RS16145 3566968..3567372 - 405 WP_102802202.1 type II toxin-antitoxin system YafO family toxin Toxin
C1O30_RS16150 3567369..3567662 - 294 WP_102802203.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
C1O30_RS16155 3568224..3569543 + 1320 WP_102802204.1 site-specific integrase -
C1O30_RS16160 3569618..3570667 - 1050 WP_102802205.1 macro domain-containing protein -
C1O30_RS16165 3570681..3571328 - 648 WP_102802206.1 DUF4433 domain-containing protein -
C1O30_RS16170 3571433..3572266 - 834 WP_102802207.1 DUF4942 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(29-132)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15494.82 Da        Isoelectric Point: 8.0873

>T91981 WP_102802202.1 NZ_CP025799:c3567372-3566968 [Dickeya zeae]
MSFRIFKSTLIRQQLSQKELDDLVVDFLSYKKEGVLPDTFGRDAPYDDDRTYPLVKEEQVAHIHLADAGAPFPKFLRQFK
RTSDQAHLVYCQGASDPDAYLLIIILKPEAHKMARNNNHMHKIGVIAEAFRMKY

Download         Length: 405 bp

>T91981 NZ_CP025799:c3567372-3566968 [Dickeya zeae]
ATGAGCTTCAGAATTTTCAAATCAACGCTTATCCGCCAGCAATTGAGCCAGAAAGAGCTGGATGATTTGGTGGTGGATTT
TCTGTCGTATAAAAAAGAGGGCGTGTTGCCGGATACCTTTGGCCGTGACGCCCCTTACGATGATGACCGTACCTACCCTC
TGGTGAAAGAAGAGCAGGTAGCGCACATTCATCTTGCTGATGCGGGTGCCCCTTTTCCTAAGTTTTTACGTCAGTTCAAG
CGAACCAGCGATCAGGCCCACTTGGTGTACTGCCAGGGTGCCAGTGATCCAGATGCCTACCTGCTCATTATCATTCTGAA
ACCCGAAGCGCATAAGATGGCGCGAAATAATAACCACATGCACAAGATAGGCGTGATAGCCGAAGCATTCAGAATGAAAT
ATTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11006.46 Da        Isoelectric Point: 4.9062

>AT91981 WP_102802203.1 NZ_CP025799:c3567662-3567369 [Dickeya zeae]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEEKQGRLHTAARFRPSAERLSEIAQNG
QTLLQNASDKDLTEFSE

Download         Length: 294 bp

>AT91981 NZ_CP025799:c3567662-3567369 [Dickeya zeae]
ATGGAACGCATTCTTGCTGAAAAATCTATCAACATCACCGAGTTAAGAAAAAACCCGGCGAAGTATTTTATTGATGAACC
GGTTGCCGTTCTCTCCAACAACCGCCCGGCTGGTTACATGGTCAGCGCTAAGGTGTTTGAAGAGCTGATCGATCTGTTGG
AAGAGAAGCAGGGTAGGTTGCATACTGCCGCGCGTTTTCGTCCAAGCGCTGAACGGTTAAGCGAGATTGCGCAGAACGGG
CAGACACTGCTGCAAAACGCCTCTGACAAGGATCTGACCGAGTTCTCTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References