Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 3383115..3383624 Replicon chromosome
Accession NZ_CP025791
Organism Flavivirga eckloniae strain ECD14

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag C1H87_RS14010 Protein ID WP_102756410.1
Coordinates 3383364..3383624 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C1H87_RS14005 Protein ID WP_102756409.1
Coordinates 3383115..3383363 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1H87_RS13985 3378631..3379548 + 918 WP_102756405.1 tryptophan 2,3-dioxygenase -
C1H87_RS13990 3379506..3380831 + 1326 WP_102756406.1 peptidoglycan DD-metalloendopeptidase family protein -
C1H87_RS13995 3380835..3382454 + 1620 WP_102756407.1 glucose-6-phosphate isomerase -
C1H87_RS14000 3382594..3382836 - 243 WP_158655226.1 hypothetical protein -
C1H87_RS14005 3383115..3383363 + 249 WP_102756409.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C1H87_RS14010 3383364..3383624 + 261 WP_102756410.1 Txe/YoeB family addiction module toxin Toxin
C1H87_RS14015 3384132..3384428 + 297 WP_158655227.1 hypothetical protein -
C1H87_RS14020 3384739..3385143 + 405 WP_102756412.1 lipocalin family protein -
C1H87_RS14025 3385526..3388063 + 2538 WP_102756413.1 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10377.01 Da        Isoelectric Point: 9.7723

>T91959 WP_102756410.1 NZ_CP025791:3383364-3383624 [Flavivirga eckloniae]
MKLTWSTSSWEEYLYWQKVDKKLVKRINELIKSCMRTPFEGIGKPEALKGDLQGYWSRRITSEHRLVYKYENDQLLIAAC
RYHYGK

Download         Length: 261 bp

>T91959 NZ_CP025791:3383364-3383624 [Flavivirga eckloniae]
ATGAAATTAACTTGGTCTACGTCTTCTTGGGAAGAGTATCTGTATTGGCAAAAAGTTGATAAGAAACTAGTAAAACGAAT
TAACGAACTCATTAAAAGTTGTATGCGAACACCTTTTGAAGGCATCGGGAAACCCGAAGCTCTAAAGGGAGATTTACAAG
GCTATTGGTCGAGGCGAATTACATCAGAACATCGATTGGTTTACAAATATGAAAATGACCAGTTATTAATTGCAGCCTGT
CGTTATCATTACGGAAAATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9501.82 Da        Isoelectric Point: 4.8232

>AT91959 WP_102756409.1 NZ_CP025791:3383115-3383363 [Flavivirga eckloniae]
METVNYTDFRSNLKHWFDKVVNDVSDIIIKRKNGKDLVLISLDEYNSLKETTYLLTGKNRDILLNSIKELEAGEGVQKDL
IE

Download         Length: 249 bp

>AT91959 NZ_CP025791:3383115-3383363 [Flavivirga eckloniae]
ATGGAAACAGTAAATTATACAGACTTTCGTTCAAATCTAAAACATTGGTTCGATAAAGTGGTCAATGATGTAAGCGATAT
CATCATCAAGCGAAAAAATGGTAAGGATCTAGTTTTAATATCGTTAGATGAGTACAACTCACTAAAAGAAACCACCTATT
TGCTTACAGGAAAAAACAGAGATATTTTATTAAACTCCATCAAAGAACTAGAAGCAGGCGAAGGTGTTCAAAAAGACTTA
ATCGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References