Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | BrnTA/BrnT-BrnA |
Location | 962125..962684 | Replicon | chromosome |
Accession | NZ_CP025743 | ||
Organism | Brucella abortus strain CIIMS-NV-4 |
Toxin (Protein)
Gene name | brnT | Uniprot ID | A0A7U8PD14 |
Locus tag | C1A46_RS05050 | Protein ID | WP_002966807.1 |
Coordinates | 962439..962684 (-) | Length | 82 a.a. |
Antitoxin (Protein)
Gene name | brnA | Uniprot ID | Q57DF1 |
Locus tag | C1A46_RS05045 | Protein ID | WP_002964097.1 |
Coordinates | 962125..962439 (-) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C1A46_RS04995 | 957817..958020 | - | 204 | WP_002964087.1 | hypothetical protein | - |
C1A46_RS05000 | 958023..958238 | - | 216 | WP_002971459.1 | hypothetical protein | - |
C1A46_RS05005 | 958235..958438 | - | 204 | WP_002964088.1 | hypothetical protein | - |
C1A46_RS05010 | 958488..959206 | + | 719 | Protein_917 | hypothetical protein | - |
C1A46_RS05015 | 959203..959433 | + | 231 | WP_002964091.1 | hypothetical protein | - |
C1A46_RS05020 | 959430..959705 | + | 276 | WP_002964092.1 | hypothetical protein | - |
C1A46_RS05025 | 959728..960204 | + | 477 | WP_002966806.1 | hypothetical protein | - |
C1A46_RS05030 | 960550..961259 | + | 710 | Protein_921 | porin family protein | - |
C1A46_RS05035 | 961607..961777 | - | 171 | WP_002964095.1 | DUF1508 domain-containing protein | - |
C1A46_RS05045 | 962125..962439 | - | 315 | WP_002964097.1 | BrnA antitoxin family protein | Antitoxin |
C1A46_RS05050 | 962439..962684 | - | 246 | WP_002966807.1 | BrnT family toxin | Toxin |
C1A46_RS05055 | 962817..963455 | + | 639 | Protein_925 | tRNA-guanine transglycosylase | - |
C1A46_RS05060 | 963525..964282 | + | 758 | WP_102040076.1 | IS5 family transposase | - |
C1A46_RS16820 | 964283..965056 | + | 774 | Protein_927 | hypothetical protein | - |
C1A46_RS05075 | 965385..966836 | + | 1452 | WP_004685623.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | wboA / wbdA | 956805..970152 | 13347 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 82 a.a. Molecular weight: 9162.82 Da Isoelectric Point: 10.3158
>T91861 WP_002966807.1 NZ_CP025743:c962684-962439 [Brucella abortus]
MKIIWDEPKRQTNIAKHGLDFADLHFEFFLSAKVFPTKADRLMAIGEFNGLIIIAVIFKPVGSEALSVISMRSASQKERK
L
MKIIWDEPKRQTNIAKHGLDFADLHFEFFLSAKVFPTKADRLMAIGEFNGLIIIAVIFKPVGSEALSVISMRSASQKERK
L
Download Length: 246 bp
>T91861 NZ_CP025743:c962684-962439 [Brucella abortus]
ATGAAGATCATCTGGGACGAACCGAAGCGACAGACCAACATTGCCAAGCACGGCTTGGACTTCGCTGACCTGCATTTCGA
ATTCTTCCTGTCGGCTAAGGTCTTCCCCACCAAGGCAGATCGCTTGATGGCAATCGGAGAATTCAACGGCCTGATTATCA
TCGCCGTCATTTTCAAGCCGGTTGGTTCGGAAGCCCTCTCCGTGATCTCCATGCGTTCAGCAAGCCAGAAGGAAAGGAAG
CTCTGA
ATGAAGATCATCTGGGACGAACCGAAGCGACAGACCAACATTGCCAAGCACGGCTTGGACTTCGCTGACCTGCATTTCGA
ATTCTTCCTGTCGGCTAAGGTCTTCCCCACCAAGGCAGATCGCTTGATGGCAATCGGAGAATTCAACGGCCTGATTATCA
TCGCCGTCATTTTCAAGCCGGTTGGTTCGGAAGCCCTCTCCGTGATCTCCATGCGTTCAGCAAGCCAGAAGGAAAGGAAG
CTCTGA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11638.42 Da Isoelectric Point: 10.3131
>AT91861 WP_002964097.1 NZ_CP025743:c962439-962125 [Brucella abortus]
MGIKFSSKRPLTQEEEAEIQKMIASDPDAPEATDEQLAKAKPFKEAFPDMAAKMEKAIRGRPRIDNPKTPVTIRLDQDVV
QRFKATGKGWQGRMNDALRKAVGL
MGIKFSSKRPLTQEEEAEIQKMIASDPDAPEATDEQLAKAKPFKEAFPDMAAKMEKAIRGRPRIDNPKTPVTIRLDQDVV
QRFKATGKGWQGRMNDALRKAVGL
Download Length: 315 bp
>AT91861 NZ_CP025743:c962439-962125 [Brucella abortus]
ATGGGTATCAAATTTTCCTCTAAGCGCCCTCTCACTCAGGAAGAAGAGGCAGAAATTCAGAAGATGATCGCAAGCGATCC
CGATGCACCGGAAGCCACCGATGAACAGCTTGCCAAGGCCAAGCCTTTCAAGGAAGCCTTTCCAGATATGGCCGCCAAGA
TGGAGAAGGCCATTCGAGGCCGGCCGCGCATCGACAATCCCAAGACGCCGGTTACTATCCGGCTCGATCAGGATGTAGTT
CAACGCTTCAAGGCCACCGGCAAAGGCTGGCAGGGCCGTATGAACGATGCCCTGCGCAAAGCTGTCGGGCTTTGA
ATGGGTATCAAATTTTCCTCTAAGCGCCCTCTCACTCAGGAAGAAGAGGCAGAAATTCAGAAGATGATCGCAAGCGATCC
CGATGCACCGGAAGCCACCGATGAACAGCTTGCCAAGGCCAAGCCTTTCAAGGAAGCCTTTCCAGATATGGCCGCCAAGA
TGGAGAAGGCCATTCGAGGCCGGCCGCGCATCGACAATCCCAAGACGCCGGTTACTATCCGGCTCGATCAGGATGTAGTT
CAACGCTTCAAGGCCACCGGCAAAGGCTGGCAGGGCCGTATGAACGATGCCCTGCGCAAAGCTGTCGGGCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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