Detailed information of TA system TA091805

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 4922866..4923237
• Replicon: chromosome
• Accession: NZ_CP025707
• Organism: Escherichia coli strain YDC107

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: A0A0D6ZRD3
• Locus tag: YDC107_RS24035
• Protein ID: WP_001443846.1
• Coordinates: 4923088..4923237 (-)
• Length: 50 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	4922866..4923044 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
YDC107_RS24010	4918821..4920194	+	1374	WP_000123748.1	ATP-dependent RNA helicase DbpA	-
YDC107_RS24015	4920323..4921258	-	936	WP_001523172.1	tRNA 2-thiocytidine(32) synthetase TtcA	-
YDC107_RS24020	4921310..4922545	-	1236	WP_000040839.1	site-specific integrase	-
YDC107_RS24025	4922547..4922762	-	216	WP_000079604.1	excisionase XisR	-
YDC107_RS24030	4922862..4923050	-	189	WP_001302840.1	DUF1187 family protein	-
-	4922866..4923044	+	179	NuclAT_0	-	Antitoxin
-	4922866..4923044	+	179	NuclAT_0	-	Antitoxin
-	4922866..4923044	+	179	NuclAT_0	-	Antitoxin
-	4922866..4923044	+	179	NuclAT_0	-	Antitoxin
YDC107_RS24035	4923088..4923237	-	150	WP_001443846.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
YDC107_RS24040	4923293..4924102	-	810	WP_000166313.1	recombination protein RecT	-
YDC107_RS24045	4924095..4926695	-	2601	WP_000105140.1	exodeoxyribonuclease VIII	-
YDC107_RS24050	4926797..4927072	-	276	WP_001344816.1	hypothetical protein	-
YDC107_RS24055	4927147..4927317	-	171	WP_001352098.1	conserved protein, Rac prophage	-
YDC107_RS24060	4927317..4927538	-	222	WP_000560223.1	killing protein KilR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	4916497..4968311	51814

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-48)

Sequences

Toxin

Protein

• Length: 50 a.a.
• Molecular weight: 5383.12 Da
• Isoelectric Point: 8.3398

>T91805 WP_001443846.1 NZ_CP025707:c4923237-4923088 [Escherichia coli]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALER

Nucleotide

• Length: 150 bp

>T91805 NZ_CP025707:c4923237-4923088 [Escherichia coli]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAACGATGA

Antitoxin

Nucleotide

• Length: 179 bp

>AT91805 NZ_CP025707:4922866-4923044 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT

Structures

Toxin

• AlphaFold DB: A0A0D6ZRD3

Antitoxin