Detailed information of TA system TA091761

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 4014085..4014307
• Replicon: chromosome
• Accession: NZ_CP025703
• Organism: Escherichia coli strain BH100N substr. MG2017

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: BH100N_RS20505
• Protein ID: WP_001295224.1
• Coordinates: 4014085..4014192 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	4014241..4014307 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BH100N_RS20480	4009338..4010090	-	753	Protein_3745	cellulose biosynthesis protein BcsQ	-
BH100N_RS20485	4010102..4010290	-	189	WP_001063314.1	YhjR family protein	-
BH100N_RS20490	4010563..4012134	+	1572	WP_001204945.1	cellulose biosynthesis protein BcsE	-
BH100N_RS20495	4012131..4012322	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
BH100N_RS20500	4012319..4013998	+	1680	WP_000191565.1	cellulose biosynthesis protein BcsG	-
BH100N_RS20505	4014085..4014192	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	4014241..4014307	+	67	-	-	Antitoxin
BH100N_RS20520	4014668..4015939	+	1272	WP_001298005.1	amino acid permease	-
BH100N_RS20525	4015969..4016973	-	1005	WP_000103577.1	dipeptide ABC transporter ATP-binding subunit DppF	-
BH100N_RS20530	4016970..4017953	-	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
BH100N_RS20535	4017964..4018866	-	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T91761 WP_001295224.1 NZ_CP025703:c4014192-4014085 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T91761 NZ_CP025703:c4014192-4014085 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 67 bp

>AT91761 NZ_CP025703:4014241-4014307 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATATTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin