Detailed information of TA system TA091675

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symE-ohsC/SymE(toxin)
• Location: 4077251..4077664
• Replicon: chromosome
• Accession: NZ_CP025676
• Organism: Escherichia albertii strain ChinaSP140150

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: C0R48_RS21040
• Protein ID: WP_059250864.1
• Coordinates: 4077323..4077664 (+)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	ohsC
Locus tag	-
Coordinates	4077251..4077328 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C0R48_RS21030	4074153..4075742	+	1590	WP_059250861.1	type I restriction-modification system methyltransferase	-
C0R48_RS21035	4075739..4077094	+	1356	WP_059274703.1	restriction endonuclease subunit S	-
-	4077251..4077328	-	78	NuclAT_8	-	Antitoxin
-	4077251..4077328	-	78	NuclAT_8	-	Antitoxin
-	4077251..4077328	-	78	NuclAT_8	-	Antitoxin
-	4077251..4077328	-	78	NuclAT_8	-	Antitoxin
-	4077251..4077328	-	78	NuclAT_9	-	Antitoxin
-	4077251..4077328	-	78	NuclAT_9	-	Antitoxin
-	4077251..4077328	-	78	NuclAT_9	-	Antitoxin
-	4077251..4077328	-	78	NuclAT_9	-	Antitoxin
C0R48_RS21040	4077323..4077664	+	342	WP_059250864.1	endoribonuclease SymE	Toxin
C0R48_RS21045	4077711..4079807	-	2097	Protein_3884	DUF262 domain-containing protein	-
C0R48_RS27345	4080032..4080205	+	174	Protein_3885	GntR family transcriptional regulator	-
C0R48_RS21050	4080357..4081289	-	933	WP_059250868.1	Rpn family recombination-promoting nuclease/putative transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12326.12 Da
• Isoelectric Point: 7.8219

>T91675 WP_059250864.1 NZ_CP025676:4077323-4077664 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTTQPPAAEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

>T91675 NZ_CP025676:4077323-4077664 [Escherichia albertii]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCTCCTGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCTA
CCGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCACCCAACCACCCGCCGCCGAAGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTATGCAAGCTGTCGGCGCGTAAACAAAAGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA

Antitoxin

Nucleotide

• Length: 78 bp

>AT91675 NZ_CP025676:c4077328-4077251 [Escherichia albertii]
AGTCATAACTGCTATTCCTTGGAAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin