Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4002514..4002772 Replicon chromosome
Accession NZ_CP025676
Organism Escherichia albertii strain ChinaSP140150

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag C0R48_RS20665 Protein ID WP_000809168.1
Coordinates 4002620..4002772 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4002514..4002571 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C0R48_RS20645 3998321..3999568 - 1248 WP_059235056.1 hypothetical protein -
C0R48_RS20650 3999722..4001215 - 1494 WP_059214855.1 sulfatase-like hydrolase/transferase -
C0R48_RS20655 4001236..4001997 - 762 WP_102204156.1 hypothetical protein -
- 4002514..4002571 - 58 - - Antitoxin
C0R48_RS20665 4002620..4002772 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
C0R48_RS20670 4002880..4004010 - 1131 WP_001118445.1 molecular chaperone DnaJ -
C0R48_RS20675 4004099..4006015 - 1917 WP_000516135.1 molecular chaperone DnaK -
C0R48_RS20685 4006390..4006794 + 405 WP_000833521.1 DUF2541 family protein -
C0R48_RS20690 4006821..4007534 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T91673 WP_000809168.1 NZ_CP025676:4002620-4002772 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T91673 NZ_CP025676:4002620-4002772 [Escherichia albertii]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT91673 NZ_CP025676:c4002571-4002514 [Escherichia albertii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References