Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 5700323..5701113 Replicon chromosome
Accession NZ_CP025624
Organism Pseudomonas sp. NC02

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag C0058_RS26790 Protein ID WP_003216329.1
Coordinates 5700323..5700634 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag C0058_RS26795 Protein ID WP_003216327.1
Coordinates 5700631..5701113 (+) Length 161 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C0058_RS26770 5696444..5697571 + 1128 WP_102369867.1 DUF1120 domain-containing protein -
C0058_RS26775 5697587..5698237 + 651 WP_102369868.1 DUF1120 domain-containing protein -
C0058_RS26780 5698234..5699514 - 1281 WP_087692825.1 CynX/NimT family MFS transporter -
C0058_RS26785 5699504..5700163 - 660 WP_003216331.1 FadR family transcriptional regulator -
C0058_RS26790 5700323..5700634 + 312 WP_003216329.1 type II toxin-antitoxin system MqsR family toxin Toxin
C0058_RS26795 5700631..5701113 + 483 WP_003216327.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
C0058_RS26800 5701175..5701939 - 765 WP_003171943.1 amino acid ABC transporter ATP-binding protein -
C0058_RS26805 5701950..5703047 - 1098 WP_003216325.1 amino acid ABC transporter permease -
C0058_RS26810 5703058..5704239 - 1182 WP_003216323.1 amino acid ABC transporter permease -
C0058_RS26815 5704312..5705343 - 1032 WP_003216321.1 amino acid ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-100)

Antitoxin

Zinc finger, MqsA-type

(6-53)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12181.92 Da        Isoelectric Point: 7.4697

>T91625 WP_003216329.1 NZ_CP025624:5700323-5700634 [Pseudomonas sp. NC02]
MEKYTPHYDLAVIKADVRRLGKQAFTQSARRCGEDLDLSIEQMQAVIFELKNTMLYKSMTTHDDHRVWQDVYHIHSHDLE
IYIKVTYRTDGKPPVISFKEKNP

Download         Length: 312 bp

>T91625 NZ_CP025624:5700323-5700634 [Pseudomonas sp. NC02]
ATGGAAAAGTACACACCTCATTACGATCTGGCGGTGATAAAGGCGGATGTCAGGCGGCTTGGAAAGCAAGCATTTACTCA
AAGCGCACGCCGTTGCGGCGAGGATCTTGATTTAAGCATCGAACAAATGCAGGCAGTCATTTTCGAGTTGAAAAACACGA
TGTTGTACAAGTCGATGACCACTCATGACGACCATCGAGTTTGGCAAGATGTGTATCACATTCACTCACATGATCTGGAG
ATCTACATCAAGGTGACCTACCGCACGGATGGTAAACCTCCGGTGATCTCCTTCAAGGAGAAAAACCCATGA

Antitoxin


Download         Length: 161 a.a.        Molecular weight: 18286.72 Da        Isoelectric Point: 6.9616

>AT91625 WP_003216327.1 NZ_CP025624:5700631-5701113 [Pseudomonas sp. NC02]
MKTEQCFSCGRHDGMHHFSGRSETSEVKGLHRRIDDLSGWECQACGEVILDPEDAERYSDHCDEIVHSFRQMVGTEMKRI
RRKLHLSQKETVQLLSGGGHNALSRYERGEVLPPKSLVVLMRLLERHPHLLVEAKILSEGADLRNSVHTVHKEHETLTTT

Download         Length: 483 bp

>AT91625 NZ_CP025624:5700631-5701113 [Pseudomonas sp. NC02]
ATGAAAACAGAGCAATGCTTCAGCTGCGGCAGGCATGACGGAATGCATCACTTCTCAGGACGTAGCGAAACATCGGAAGT
CAAAGGTTTGCATCGCCGTATAGACGATCTGTCTGGATGGGAGTGCCAGGCATGTGGAGAGGTGATCCTGGACCCCGAAG
ACGCGGAACGCTATTCAGACCACTGCGATGAAATCGTTCACAGTTTCAGGCAGATGGTCGGCACCGAGATGAAGCGCATA
CGCCGCAAACTGCACCTTTCACAAAAAGAAACGGTACAACTGCTATCGGGTGGCGGCCACAACGCCTTATCTCGCTACGA
GCGCGGTGAGGTATTGCCCCCCAAATCCCTGGTAGTCCTGATGCGTTTGCTTGAGCGTCACCCCCACTTGCTGGTCGAAG
CAAAAATCCTGAGTGAAGGCGCAGATCTTCGCAATTCCGTGCATACGGTACATAAAGAGCACGAGACCCTGACGACAACT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References