Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1743301..1743815 Replicon chromosome
Accession NZ_CP025611
Organism Niveispirillum cyanobacteriorum strain TH16

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag C0V82_RS07910 Protein ID WP_102111865.1
Coordinates 1743301..1743567 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C0V82_RS07915 Protein ID WP_102111866.1
Coordinates 1743564..1743815 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C0V82_RS07885 1738507..1739160 + 654 WP_102111861.1 hypothetical protein -
C0V82_RS07890 1739219..1740427 - 1209 WP_102111862.1 DUF418 domain-containing protein -
C0V82_RS27240 1740638..1740799 + 162 WP_188595060.1 hypothetical protein -
C0V82_RS07895 1740855..1742336 - 1482 WP_102111863.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
C0V82_RS07900 1742336..1742638 - 303 WP_054165863.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
C0V82_RS07905 1742736..1743245 + 510 WP_102111864.1 Holliday junction resolvase RuvX -
C0V82_RS07910 1743301..1743567 - 267 WP_102111865.1 Txe/YoeB family addiction module toxin Toxin
C0V82_RS07915 1743564..1743815 - 252 WP_102111866.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C0V82_RS07920 1743877..1747479 - 3603 WP_102111867.1 hydantoinase B/oxoprolinase family protein -
C0V82_RS07925 1747685..1748476 + 792 WP_158659803.1 LytTR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10075.51 Da        Isoelectric Point: 9.6565

>T91611 WP_102111865.1 NZ_CP025611:c1743567-1743301 [Niveispirillum cyanobacteriorum]
MKVVFSEAAWDDYLAWQAQHPEIVGRINDLLQSARRTPFTGIGKPEPLKGPLSGFWSRRITQEHRLVYQVAGAGPDQRIE
VLSCRKHY

Download         Length: 267 bp

>T91611 NZ_CP025611:c1743567-1743301 [Niveispirillum cyanobacteriorum]
ATGAAGGTCGTCTTTTCTGAGGCGGCTTGGGACGACTATCTGGCATGGCAGGCCCAGCACCCGGAGATTGTTGGGCGTAT
CAACGATTTGCTGCAAAGCGCCCGGCGCACGCCCTTCACCGGTATCGGCAAGCCTGAGCCATTGAAGGGTCCGCTGAGCG
GCTTTTGGTCCCGCCGGATCACCCAGGAGCACCGCCTCGTGTATCAGGTAGCTGGTGCCGGCCCGGATCAGCGGATAGAG
GTTTTGTCTTGCCGCAAGCACTATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9383.54 Da        Isoelectric Point: 4.3988

>AT91611 WP_102111866.1 NZ_CP025611:c1743815-1743564 [Niveispirillum cyanobacteriorum]
MDVVNYSTARQNLAGLMDKVTQDRTPVVVTRQGAEDVILMSMSEFEGWQETVHLLSSPANAEHLRRSMEQLDAGRIVEWN
PPE

Download         Length: 252 bp

>AT91611 NZ_CP025611:c1743815-1743564 [Niveispirillum cyanobacteriorum]
ATGGATGTGGTGAATTACAGCACAGCCCGACAGAATTTGGCGGGCCTTATGGACAAGGTTACACAGGATCGAACGCCTGT
CGTGGTGACGCGCCAAGGTGCCGAGGATGTGATTTTAATGTCCATGAGTGAGTTCGAGGGGTGGCAGGAGACGGTTCACC
TGCTCAGTTCACCCGCGAACGCGGAACATCTGCGGCGATCCATGGAACAATTGGATGCGGGCCGGATCGTTGAATGGAAC
CCGCCTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References