Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2094077..2094592 Replicon chromosome
Accession NZ_CP025570
Organism Acidipropionibacterium jensenii strain JS280

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag C0Z10_RS09410 Protein ID WP_097799199.1
Coordinates 2094077..2094331 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A3S4UWW3
Locus tag C0Z10_RS09415 Protein ID WP_028702687.1
Coordinates 2094332..2094592 (-) Length 87 a.a.

Genomic Context

C0Z10_RS09380C0Z10_RS09385C0Z10_RS09390C0Z10_RS09395C0Z10_RS09400C0Z10_RS09405C0Z10_RS09410C0Z10_RS09415C0Z10_RS09420C0Z10_RS09425C0Z10_RS09430C0Z10_RS09435C0Z10_RS09440C0Z10_RS09445C0Z10_RS09450C0Z10_RS09455
Location: 2089158..2089685 (528 bp)
Type: Others
Protein ID: WP_201270069.1
Location: 2089682..2090059 (378 bp)
Type: Others
Protein ID: WP_097799194.1
Location: 2090146..2090745 (600 bp)
Type: Others
Protein ID: WP_097799195.1
Location: 2090762..2092642 (1881 bp)
Type: Others
Protein ID: WP_201270186.1
Location: 2092686..2093240 (555 bp)
Type: Others
Protein ID: WP_127822683.1
Location: 2093288..2093827 (540 bp)
Type: Others
Protein ID: WP_097799198.1
Location: 2094077..2094331 (255 bp)
Type: Toxin
Protein ID: WP_097799199.1
Location: 2094332..2094592 (261 bp)
Type: Antitoxin
Protein ID: WP_028702687.1
Location: 2094874..2095128 (255 bp)
Type: Others
Protein ID: WP_201270187.1
Location: 2095170..2095328 (159 bp)
Type: Others
Protein ID: WP_097799906.1
Location: 2095532..2096674 (1143 bp)
Type: Others
Protein ID: WP_097799200.1
Location: 2096888..2097385 (498 bp)
Type: Others
Protein ID: WP_097799201.1
Location: 2097715..2098068 (354 bp)
Type: Others
Protein ID: WP_097799202.1
Location: 2098290..2098751 (462 bp)
Type: Others
Protein ID: WP_097799203.1
Location: 2098748..2098981 (234 bp)
Type: Others
Protein ID: WP_097799204.1
Location: 2098995..2099282 (288 bp)
Type: Others
Protein ID: WP_097799205.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C0Z10_RS093802089158..2089685-528WP_201270069.1methylated-DNA--[protein]-cysteine S-methyltransferase-
C0Z10_RS093852089682..2090059-378WP_097799194.1DUF1801 domain-containing protein-
C0Z10_RS093902090146..2090745-600WP_097799195.1histone deacetylase-
C0Z10_RS093952090762..2092642-1881WP_201270186.1ABC transporter ATP-binding protein/permease-
C0Z10_RS094002092686..2093240-555WP_127822683.1hypothetical protein-
C0Z10_RS094052093288..2093827-540WP_097799198.1GNAT family N-acetyltransferase-
C0Z10_RS094102094077..2094331-255WP_097799199.1Txe/YoeB family addiction module toxinToxin
C0Z10_RS094152094332..2094592-261WP_028702687.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
C0Z10_RS094202094874..2095128-255WP_201270187.1HigA family addiction module antidote protein-
C0Z10_RS094252095170..2095328-159WP_097799906.1type II toxin-antitoxin system RelE/ParE family toxin-
C0Z10_RS094302095532..2096674-1143WP_097799200.1phage major capsid protein-
C0Z10_RS094352096888..2097385-498WP_097799201.1hypothetical protein-
C0Z10_RS094402097715..2098068-354WP_097799202.1WhiB family transcriptional regulator-
C0Z10_RS094452098290..2098751-462WP_097799203.1hypothetical protein-
C0Z10_RS094502098748..2098981-234WP_097799204.1hypothetical protein-
C0Z10_RS094552098995..2099282-288WP_097799205.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9914.25 Da        Isoelectric Point: 8.0424

>T90559 WP_097799199.1 NZ_CP025570:c2094331-2094077 [Acidipropionibacterium jensenii]
VRLVWDPSAWEDYTHWQTTDRRVLKRINTLIGSCLREPFAGIGKPEQLKYGAQGAWSRRITDEHRLVYLVDGDDLVILQA
RYHY

Download         Length: 255 bp

>T90559 NZ_CP025570:c2094331-2094077 [Acidipropionibacterium jensenii]
GTGCGGCTGGTCTGGGACCCGTCTGCATGGGAGGACTACACACACTGGCAGACCACCGATCGTCGCGTGCTGAAGCGAAT
CAACACGCTCATCGGCTCCTGCCTTCGTGAGCCGTTCGCGGGTATCGGGAAACCGGAGCAGTTGAAGTATGGCGCGCAGG
GGGCATGGTCGCGCCGTATCACCGATGAGCACCGGCTGGTGTATCTCGTCGACGGGGACGACCTCGTGATCCTCCAGGCC
CGCTACCACTACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9780.93 Da        Isoelectric Point: 4.8839

>AT90559 WP_028702687.1 NZ_CP025570:c2094592-2094332 [Acidipropionibacterium jensenii]
MSISASEARRTLFPLIERINEDREAIEIVSRKGNAVLMPADEYTAWQETAYLFRSPANARRLLDAYERARAGKVETHALD
RADEDA

Download         Length: 261 bp

>AT90559 NZ_CP025570:c2094592-2094332 [Acidipropionibacterium jensenii]
ATGTCTATCAGTGCCAGCGAGGCGCGCAGGACGCTGTTCCCGCTCATTGAGCGCATCAATGAAGACCGCGAGGCCATCGA
GATCGTCTCCCGCAAGGGCAACGCAGTGTTGATGCCCGCCGACGAGTACACGGCCTGGCAGGAGACGGCCTATCTGTTCC
GCTCACCTGCGAATGCTCGGCGACTGCTCGATGCCTACGAGCGTGCCCGCGCTGGGAAGGTCGAGACGCATGCCCTCGAC
CGTGCGGACGAGGATGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3S4UWW3

References