Detailed information of TA system TA090447

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2315582..2315764
• Replicon: chromosome
• Accession: NZ_CP025495
• Organism: Staphylococcus aureus strain 3020.C01

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: A7U46_RS15375
• Protein ID: WP_001801861.1
• Coordinates: 2315669..2315764 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2315582..2315641 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7U46_RS12250	2314720..2315097	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
A7U46_RS12255	2315291..2315467	+	177	Protein_2254	transposase	-
A7U46_RS12260	2315445..2315546	-	102	WP_001791893.1	hypothetical protein	-
-	2315582..2315641	+	60	-	-	Antitoxin
A7U46_RS15375	2315669..2315764	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
A7U46_RS12270	2315967..2316110	+	144	WP_001549059.1	transposase	-
A7U46_RS12280	2316714..2317097	+	384	WP_000070811.1	hypothetical protein	-
A7U46_RS12285	2317108..2317284	+	177	WP_000375476.1	hypothetical protein	-
A7U46_RS12290	2317286..2317471	+	186	WP_000809857.1	hypothetical protein	-
A7U46_RS12295	2317585..2318226	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
A7U46_RS12300	2318444..2318995	-	552	WP_000414205.1	hypothetical protein	-
A7U46_RS12305	2319093..2319437	-	345	WP_000627551.1	DUF3969 family protein	-
A7U46_RS12310	2319478..2320104	-	627	Protein_2264	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	2282493..2353217	70724

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T90447 WP_001801861.1 NZ_CP025495:c2315764-2315669 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T90447 NZ_CP025495:c2315764-2315669 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT90447 NZ_CP025495:2315582-2315641 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin