90438

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1979891..1980170 Replicon chromosome
Accession NZ_CP025495
Organism Staphylococcus aureus strain 3020.C01

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag A7U46_RS10175 Protein ID WP_001802298.1
Coordinates 1979891..1979995 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1979991..1980170 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7U46_RS10150 1975275..1976057 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
A7U46_RS10155 1976125..1976982 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
A7U46_RS10160 1977687..1977779 - 93 WP_001790138.1 hypothetical protein -
A7U46_RS10165 1978068..1979204 + 1137 WP_000115564.1 SAP domain-containing protein -
A7U46_RS15440 1979247..1979730 + 484 Protein_1903 recombinase family protein -
A7U46_RS10175 1979891..1979995 + 105 WP_001802298.1 hypothetical protein Toxin
- 1979991..1980170 - 180 - - Antitoxin
A7U46_RS10180 1980495..1981586 - 1092 WP_000495671.1 lytic regulatory protein -
A7U46_RS10185 1981852..1982832 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
A7U46_RS10190 1982834..1983154 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
A7U46_RS10195 1983306..1983971 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T90438 WP_001802298.1 NZ_CP025495:1979891-1979995 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T90438 NZ_CP025495:1979891-1979995 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
CAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT90438 NZ_CP025495:c1980170-1979991 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References