Detailed information of TA system TA090265

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2519876..2520024
• Replicon: chromosome
• Accession: NZ_CP025396
• Organism: Staphylococcus haemolyticus strain B

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: CYD28_RS12775
• Protein ID: WP_011276848.1
• Coordinates: 2519929..2520024 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2519876..2519911 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CYD28_RS12215	2515552..2515689	-	138	Protein_2347	NAD(P)H-dependent oxidoreductase	-
CYD28_RS12220	2515831..2516961	-	1131	WP_033080168.1	NADH-dependent flavin oxidoreductase	-
CYD28_RS12225	2517163..2517585	-	423	WP_033080167.1	MarR family transcriptional regulator	-
CYD28_RS12230	2518229..2518831	-	603	WP_011276850.1	hypothetical protein	-
CYD28_RS12235	2519043..2519735	-	693	WP_103416071.1	nucleotidyltransferase	-
-	2519876..2519911	-	36	-	-	Antitoxin
CYD28_RS12775	2519929..2520024	-	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
CYD28_RS12780	2520219..2520467	-	249	WP_002440480.1	hypothetical protein	-
CYD28_RS12240	2520489..2520793	-	305	Protein_2354	hypothetical protein	-
CYD28_RS12245	2520932..2521315	-	384	WP_011276846.1	effector binding domain-containing protein	-
CYD28_RS12250	2521555..2522085	-	531	WP_011276845.1	N-acetyltransferase	-
CYD28_RS12905	2522689..2522946	-	258	Protein_2357	replication initiation protein	-
CYD28_RS12265	2523639..2523956	+	318	Protein_2358	IS200/IS605-like element ISSep3 family transposase	-
CYD28_RS12270	2524064..2524297	-	234	WP_016931184.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2523639..2523959	320

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T90265 WP_011276848.1 NZ_CP025396:c2520024-2519929 [Staphylococcus haemolyticus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T90265 NZ_CP025396:c2520024-2519929 [Staphylococcus haemolyticus]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT90265 NZ_CP025396:c2519911-2519876 [Staphylococcus haemolyticus]
TACAACAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin