Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1870151..1870331 Replicon chromosome
Accession NZ_CP025395
Organism Staphylococcus aureus O46

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SAO46_RS14325 Protein ID WP_001801861.1
Coordinates 1870151..1870246 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1870274..1870331 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAO46_RS09255 1865219..1865791 + 573 WP_000414228.1 hypothetical protein -
SAO46_RS09260 1866167..1867003 + 837 WP_000190484.1 ABC transporter ATP-binding protein -
SAO46_RS09270 1867809..1867994 - 186 WP_000809858.1 hypothetical protein -
SAO46_RS09275 1867996..1868172 - 177 WP_000375476.1 hypothetical protein -
SAO46_RS09280 1868183..1868566 - 384 WP_000070811.1 hypothetical protein -
SAO46_RS09285 1869253..1869699 - 447 WP_000747809.1 DUF1433 domain-containing protein -
SAO46_RS14325 1870151..1870246 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1870274..1870331 - 58 - - Antitoxin
SAO46_RS09295 1870369..1870470 + 102 WP_001791232.1 hypothetical protein -
SAO46_RS09300 1870508..1870624 - 117 Protein_1762 transposase -
SAO46_RS09305 1871133..1875244 - 4112 Protein_1763 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1861550..1891572 30022


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T90253 WP_001801861.1 NZ_CP025395:1870151-1870246 [Staphylococcus aureus O46]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T90253 NZ_CP025395:1870151-1870246 [Staphylococcus aureus O46]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT90253 NZ_CP025395:c1870331-1870274 [Staphylococcus aureus O46]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References